: Turner Lab

Publications

Nighot M, Liao PL, Morris N, McCarthy D, Dharmaprakash V, Ullah Khan I, Dalessio S, Saha K, Ganapathy AS, Wang A, Ding W, Yochum G, Koltun W, Nighot P, Ma T. Long-Term Use of Proton Pump Inhibitors Disrupts Intestinal Tight Junction Barrier and Exaggerates Experimental Colitis. J Crohns Colitis. 2023 Apr 19;17(4):.. 2023. Journal of Crohn's and Colitis. 17(4), 565-579. PMCID: PMC10115233
PUBMED
Irie M, Kabata H, Fukunaga K.. Lentiviral vector-based gene transfection on human ILC2s. 2023. STAR Protocols. 5, 102854. PMC10846376
Campbell IW, Hullahalli K, Turner JR, Waldor MK. . 2023. 123, 15. PMC9884216
PUBMED
Waldow A, Beier LS, Arndt J, Schallenberg S, Vollbrecht C, Bischoff P, Farrera-Sal M, Loch FN, Bojarski C, Schumann M, Winkler L, Kamphues C, Ehlen L, Piontek J. cCPE Fusion Proteins as Molecular Probes to Detect Claudins and Tight Junction Dysregulation in Gastrointestinal Cell Lines, Tissue Explants and Patient-Derived Organoids. 2023. Pharmaceutics. 15
PUBMED
Yi Liu, Yin Zhou, Chenyu Chu, Xian Jiang. The role of macrophages in rosacea: implications for targeted therapies. 2023. Frontiers in Immunology. Aug 24:14, 1211953. PMCID: PMC10484341
PUBMED
Yi Liu, Changlan Xiang, Zhenni Que, Chenglong Li, Wen Wang, Lijuan Yin, Chenyu Chu, Yin Zhou. Neutrophil heterogeneity and aging: implications for COVID-19 and wound healing.. 2023. Frontiers in Immunology. Nov 28:14, 1201651. PMCID: PMC10715311
PUBMED
Shen W, Yang L, Yang Y, et al.. PRDX6 promotes fatty acid oxidation via PLA2-dependent PPARα activation in rats fed high-fat diet[J]. Antioxidants & Redox Signaling,. 2023. Antioxidants & Redox Signaling
PUBMED
Saha K, Subramenium Ganapathy A, Wang A, Arumugam P, Michael Morris N, Harris L, Yochum G, Koltun W, Perdew GH, Nighot M, Ma T, Nighot P. Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation.. 2023. Mucosal Immunology. 16(6), 826-842. PMC10809159
PUBMED
Yang L, Shen W, Shao W, et al.. MANF ameliorates DSS-induced mouse colitis via restricting Ly6ChiCX3CR1int macrophage transformation and suppressing CHOP-BATF2 signaling pathway. 2023. Acta Pharmacologica Sinica
PUBMED
Irie M, Kabata H, Sasahara K, Kurihara M, Shirasaki Y, Kamatani T, Baba R, Matsusaka M, Koga S, Masaki K, Miyata J, Araki Y, Kikawada T, Kabe Y, Suematsu M, Yamagishi M, Uemura S, Moro K, Fukunaga K.. Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s.. 2023. Cell Rep.. 42, 112610
Yumiko Tanaka, Mai Yamagishi, Yasutaka Motomura, Takashi Kamatani, Yusuke Oguchi, Nobutake Suzuki, Tsuyoshi Kiniwa, Hiroki Kabata, Misato Irie, Tatsuhiko Tsunoda, Fuyuki Miya, Keisuke Goda, Osamu Ohara, Takashi Funatsu, Koichi Fukunaga, Kazuyo Moro, Sotaro Uemura, Yoshitaka Shirasaki. Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation. 2023. Commun Biol.. 6, 915. 10482971
Kurihara M, Kabata H, Irie M, Fukunaga K.. Current summary of clinical studies on anti-TSLP antibody, Tezepelumab, in asthma. 2023. Allergol Int.. 72, 24-30
Abtahi S, Sailer A, Roland JT, Haest X, Chanez-Paredes SD, Ahmad K, Sadiq K, Iqbal NT, Ali SA*, Turner JR*. Intestinal epithelial digestive, transport, and barrier protein expression is increased in environmental enteric dysfunction. 2023. Lab Invest. 103, 100036
PDF
Ganapathy AS, Saha K, Wang A, Arumugam P, Dharmaprakash V, Yochum G, Koltun W, Nighot M, Perdew G, Thompson TA, Ma T, Nighot P. Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways. 2023. Cell Reports. 42(7), 112705. PMCID: PMC10528852
PUBMED
Beier, L. S. Waldow, A. Khomeijani Farahani, S. Mannweiler, R. Vidal, Y. Sy S. Brandner, J. M. Piontek, J. Gunzel, D.. Claudin targeting as an effective tool for directed barrier modulation of the viable epidermis. 2022. Annals of the New York Academy of Sciences. 1517, 251 - 265
PUBMED
Beier LS, Piontek J, Piontek A, Protze J, Kobelt D, Walther W. Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified Clostridium perfringens enterotoxin (CPE). 2022. Gene Therapy of Cancer - Methods and Protocols. 9
Zuo L, Kuo WT, Cao F, Chanez-Paredes SD, Zeve D, Mannam P, Jean-Francois L, Day A, Vallen Graham W, Sweat YY, Shashikanth N, Breault DT, Turner JR. Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease. 2022. Gut
PDF PUBMED
Enkai Li, Nathan Horn, Kolapo M Ajuwon. EPA and DHA inhibit endocytosis of claudin-4 and protect against deoxynivalenol-induced intestinal barrier dysfunction through PPARγ dependent and independent pathways in jejunal IPEC-J2 cells. 2022. Food Research International. 157, 111420
PUBMED
Maeda K, Zachos NC, Orzalli MH, Schmieder SS, Chang D, Bugda Gwilt K, Doucet M, Baetz NW, Lee S, Crawford SE, Estes MK, Kagan JC, Turner JR, Lencer WI. Depletion of the Apical Endosome in Response to Viruses and Bacterial Toxins Provides Cell-Autonomous Host Defense at Mucosal Surfaces. 2022. Cell Host Microbe. 30, 216-231 e215. PMC8852832
PDF PUBMED
Ganapathy AS, Saha K, Suchanec E, Singh V, Verma A, Yochum G, Koltun W, Nighot M, Ma T, Nighot P. AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability. 2022. Autophagy. 18(9), 2086-2103. PMC9466623
PUBMED
Saha K, Subramenium Ganapathy A, Wang A, Michael Morris N, Suchanec E, Ding W, Yochum G, Koltun W, Nighot M, Ma T, Nighot P. Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux. 2022. Journal of Crohn's and Colitis. 17(3), :433-449. PMC10069622
PUBMED
Mikolajczyk AE, Cohen NA, Watson S, Ackerman M, Goeppinger SR, Hart J, Turner JR, Rubin DT. Assessment of the Degree of Variation of Histologic Inflammation in Ulcerative Colitis. 2022. Inflamm Bowel Dis
PDF PUBMED
Zuo L, Kuo WT, Cao F, Chanez-Paredes SD, Zeve D, Mannam P, Jean-Francois L, Day A, Vallen Graham W, Sweat YY, Shashikanth N, Breault DT, Turner JR. Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease. 2022. Gut
PDF PUBMED
Vasileva E, Spadaro D, Rouaud F, King JM, Flinois A, Shah J, Sluysmans S, Mean I, Jond L, Turner JR, Citi S. Cingulin Binds to the ZU5 Domain of Scaffolding Protein Zo-1 to Promote Its Extended Conformation, Stabilization, and Tight Junction Accumulation. 2022. J Biol Chem. 298, 101797. PMC9010756
PDF PUBMED
Kuo WT, Odenwald MA, Turner JR, Zuo L. Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival. 2022. Ann N Y Acad Sci
PDF PUBMED
Shashikanth N, France MM, Xiao R, Haest X, Rizzo HE, Yeste J, Reiner J, Turner JR. Tight junction channel regulation by interclaudin interference. 2022. Nat Commun. 13, 3780
PDF PUBMED
Yuhan Yang, Yin Zhou, Chen Zhou, Xuelei Ma. Novel computer aided diagnostic models on multimodality medical images to differentiate well differentiated liposarcomas from lipomas approached by deep learning methods.. 2022. Orphanet Journal of Rare Diseases. Apr 7;17(1), 158. PMCID: PMC8991509
PUBMED
Yuhan Yang, Yin Zhou, Chen Zhou, Xuemei Zhang, Xuelei Ma. MRI-Based Computer-Aided Diagnostic Model to Predict Tumor Grading and Clinical Outcomes in Patients With Soft Tissue Sarcoma.. 2022. Journal of Magnetic Resonance Imaging. Dec;56(6), 1733-1745. PMID: 35303756
PUBMED
Yuhan Yang, Yin Zhou, Chen Zhou, Xuelei Ma. Deep learning radiomics based on contrast enhanced computed tomography predicts microvascular invasion and survival outcome in early stage hepatocellular carcinoma.. 2022. European Journal of Surgical Oncology. May;48(5), 1068-1077. PMID: 34862094
PUBMED
Abraham C, Abreu MT, Turner JR. Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease. 2022. Gastroenterology. 162, 1602-1616. PMC9112237
PDF PUBMED
Abraham C, Abreu MT, Turner JR. Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel. 2022. Gastroenterol. 162, 1602-1616 e1606. PMC9112237
PDF PUBMED
Sweat YY, Abtahi S, Chanez-Paredes SD, Raju P, Zuo L, Shashikanth N , Kuo W-T, Turner JR. Modulation of Intestinal Disorders by Claudin-2 and Occludin Via Canonical and Noncanonical Mechanisms. 2022. Tight Junctions, 3rd Edition. González-Mariscal L, Editor . 85-107
PUBMED
Yin Zhou. Comment on: Pathophysiological mechanisms of ALPPS: experimental model.. 2022. British Journal of Surgery. Dec 13;110(1), 117. PMID: 36512520
PUBMED
Kurihara M, Masaki K, Matsuyama E, Fujioka M, Hayashi R, Tomiyasu S, Sasahara K, Sunata K, Asaoka M, Akiyama Y, Nishie M, Irie M, Tanosaki T, Kabata H, Fukunaga K. How Can Dupilumab Cause Eosinophilic Pneumonia?. 2022. Biomolecules. 12, 1743. 9775034
Rie Baba, Hiroki Kabata, Yoshitaka Shirasaki, Takashi Kamatani, Mai Yamagishi, Misato Irie, Risa Watanabe, Masako Matsusaka, Katsunori Masaki, Jun Miyata, Kazuyo Moro, Sotaro Uemura, Koichi Fukunaga. Upregulation of IL-4 receptor signaling pathway in circulating ILC2s from asthma patients. 2022. J Allergy Clin Immunol Glob. 1, 299–304. 10509846
Irie M, Sasahara K, Artis D, Kabata H.. Current overview of the role of neuropeptides in ILC2s and future directions.. 2022. Allergol Int. 71, 294-300
Yeste J, Illa X, Shashikanth N, Guimera Brunet A, Villa R, Turner JR. Epithelial Monolayer Development and Tight Junction Assembly on Nanopillar Arrays. 2022. BioRxiv
PDF
Sweat YY, Turner JR. PTPN2 mutations cause epithelium-intrinsic barrier loss that synergizes with mucosal immune hyperactivation. 2021. J Clin Invest. 131, e151414. PMC8409575
PDF PUBMED
Abtahi S, Gliksman NR, Heneghan JF, Nilsen SP, Muhlich JL, Copeland J, Rozbicki E, Allan C, Dudeja PK, Turner JR. A simple method for creating a high‐content microscope for imaging multiplexed tissue microarrays. 2021. Current Protocols. 1, 68. PMC8103673
SUMMARY PDF PUBMED
Kuo WT, Zuo L, Odenwald MA, Madha S, Singh G, Gurniak CB, Abraham C, Turner JR. The Tight Junction Protein ZO-1 is Dispensable for Barrier Function but Critical for Effective Mucosal Repair. 2021. Gastroenterol. 161, 1924-1939. PMC8605999
PDF PUBMED
Huang YJ, Lee TC, Pai YC, Lin BR, Turner JR, Yu LC. A Novel Tumor Suppressor Role of Myosin Light Chain Kinase Splice Variants Through Downregulation of the TEAD4/CD44 Axis. 2021. Carcinogenesis. 42, 961-974. PMC8283729
PDF PUBMED
Shashikanth N, Rizzo HE, Pongkorpsakol P, Heneghan JF, Turner JR. Electrophysiologic Analysis of Tight Junction Size and Charge Selectivity. 2021. Curr Protoc. 1, e143. PMC8541820
PDF PUBMED
Grey MJ, Luca HD, Ward DV, Kreulen IAM, Foley SE, Thiagarajah JR, McCormick BA, Turner JR, Lencer WI. The epithelial-specific ER stress sensor IRE1β enables host-microbiota crosstalk to affect colon goblet cell development. 2021. bioRxiv
PUBMED
Ye S, Matthan NR, Lamon-Fava S, Solano-Aguilar G, Turner JR, Walker ME, Chai Z, Lakshman S, Chen C, Dawson H, Urban JF, Jr., Lichtenstein AH. Colon Transcriptome is Modified by a Dietary Pattern/Atorvastatin Interaction in the Ossabaw Pig. 2021. J Nutr Biochem. 90, 108570. PMC8994518
PDF PUBMED
Ye S, Matthan NR, Lamon-Fava S, Aguilar GS, Turner JR, Walker ME, Chai Z, Lakshman S, Urban JF, Jr., Lichtenstein AH. Western and Heart Healthy Dietary Patterns Differentially Affect the Expression of Genes Associated with Lipid Metabolism, Interferon Signaling and Inflammation in the Jejunum of Ossabaw Pigs. 2021. J Nutr Biochem. 90, 108577. PMC8982565
PDF PUBMED
Chanez-Paredes SD, Abtahi S, Kuo WT, Turner JR. Differentiating Between Tight Junction-Dependent and Tight Junction-Independent Intestinal Barrier Loss In Vivo. 2021. Methods in Molecular Biology. 2367, 249-271. PMC8249353
PDF PUBMED
Caron TJ, Scott KE, Sinha N, Muthupalani S, Baqai M, Ang LH, Li Y, Turner JR, Fox JG, Hagen SJ. Claudin-18 loss alters transcellular chloride flux but not tight junction ion selectivity in gastric epithelial cells. 2021. Cell Mol Gastroenterol Hepatol. 11, 783-801. PMC7847960
PDF PUBMED
Stevens TW, Gecse K, Turner JR, de Hertogh G, Rubin DT, D'Haens GR. Diagnostic accuracy of fecal calprotectin concentration in evaluating therapeutic outcomes of patients with ulcerative colitis. 2021. Clin Gastroenterol Hepatol. 19, 2333-2342. PMCID: PMC8140548
PDF PUBMED
Isidro R, Turner J. A commentary on: Early Change in Epithelial Neutrophilic Infiltrate Predicts Long-Term Response to Biologics in Ulcerative Coliti. 2021. PracticeUpdate
PUBMED
Yvellez OV, Rai V, Sossenheimer PH, Hart J, Turner JR, Weber C, El Jurdi K, Rubin DT. Cumulative histologic inflammation predicts colorectal neoplasia in ulcerative colitis: a validation study. 2021. Inflamm Bowel Dis. Jan 19, 203-206. 7813748
PDF PUBMED
Yin Zhou, Libin Huang. Comment on: Systemic versus oral and systemic antibiotic prophylaxis (SOAP) study in colorectal surgery: prospective randomized multicentre trial. 2021. British Journal of Surgery. Dec 1;108(12), e413. PMID: 34418049
PUBMED
Tanosaki T, Kabata H, Matsusaka M, Miyata J, Masaki K, Mochimaru T, Okuzumi S, Kuwae M, Watanabe R, Suzuki Y, Sayama K, Izuhara K, Asano K, Fukunaga K.. Clinical characteristics of patients with not well-controlled severe asthma in Japan: Analysis of the Keio Severe Asthma Research Program in Japanese population (KEIO-SARP) registry.. 2021. Allergol Int.. 70, 61-67
Okuzumi S, Miyata J, Kabata H, Mochimaru T, Kagawa S, Masaki K, Irie M, Morita H, Fukunaga K.. TLR7 Agonist Suppresses Group 2 Innate Lymphoid Cell-mediated Inflammation via IL-27-Producing Interstitial Macrophages. 2021. Am J Respir Cell Mol Biol.. 65, 309-318
Nighot M, Ganapathy AS, Saha K, Suchanec E, Castillo EF, Gregory A, Shapiro S, Ma T, Nighot P. Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis. 2021. Journal of Crohn's and Colitis. 15(10), 1751-1765. PMC8495490
PUBMED
Enkai Li, Kolapo M Ajuwon. Mechanism of endocytic regulation of intestinal tight junction remodeling during nutrient starvation in jejunal IPEC-J2 cells. 2021. The FASEB Journal. 35, e21356
PUBMED
Enkai Li, Nathan Horn, Kolapo M Ajuwon. Mechanisms of deoxynivalenol-induced endocytosis and degradation of tight junction proteins in jejunal IPEC-J2 cells involve selective activation of the MAPK pathways. 2021. Archives of Toxicology. 95, 2065-2079
PUBMED
Vetter A, Beier LS, Bouameur JE, Magin TM.. Keratins Modulate Cellular Reduction‒Oxidation Homeostasis and Mitochondrial Dynamics. 2021. Journal of Investigative Dermatology
PUBMED
Kristina Schaedlich, Laura-Sophie Beier, Judith Kolbe, Martin Wabitsch, Jana Ernst. Pro-inflammatory effects of DEHP in SGBS-derived adipocytes and THP-1 macrophages. 2021. Scientific Reports. 11
PUBMED
Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Myeloid cell expression of LACC1 is required for bacterial clearance and control of intestinal inflammation. 2020. Gastroenterology. 159, 1051-1067
PDF PUBMED
Yi Liu, Yin Zhou. The potential use of hemostatic spray powder TC-325 in pediatric patients with GI bleeding.. 2020. Gastrointestinal Endoscopy. Feb;91(2), 458. PMID: 32036954
PUBMED
Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C. T cell-intrinsic IRF5 regulates T cell signaling, migration, and differentiation and promotes intestinal inflammation. 2020. Cell Rep. 31, 107820. PMC7409536
PDF PUBMED
Inczefi O, Bacquie V, Olier-Pierre M, Rincel M, Ringot-Destrez B, Ellero-Simatos S, Eutamene H, Betoulieres C, Thomas J, Laine J, Gros L, Leveque M, Leonard R, Harkat C, Robbe-Masselot C, Roka R, Mercier-Bonin M, Theodorou V, Darnaudery M, Turner JR, Ferrier L. Targeted intestinal tight junction hyperpermeability alters the microbiome, behavior, and visceromotor responses. 2020. Cell Mol Gastroenterol Hepatol. 10, 206-208 e203. PMC7296230
SUMMARY PDF PUBMED
Donowitz M, Turner JR, Verkman AS, Zachos NC. Current and potential future applications of human stem cell models in drug development. 2020. J Clin Invest. 130, 3342-3344. PMC7324189
PDF PUBMED
Labarta-Bajo L, Nilsen SP, Humphrey G, Schwartz T, Sanders K, Swafford A, Knight R, Turner JR, Zuniga EI. Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection. 2020. J Exp Med. 217, e20192276
PDF PUBMED
Li HS, Xu SF, Sheng JY, Jiang ZH, Wang J, Ding N, Wang T, Odenwald MA, Turner JR, He WQ, Xu H, Zha JM. Quantification of proliferative and dead cells in enteroids. 2020. J Vis Exp
PUBMED
Pai YC, Weng LT, Wei SC, Wu LL, Shih DQ, Targan SR, Turner JR, Yu LC. Gut microbial transcytosis induced by tumor necrosis factor-like 1a-dependent activation of a myosin light chain kinase splice variant contributes to IBD. 2020. J Crohns Colitis. 15, 258–272. PMC7904084
PDF PUBMED
Rutlin M, Rastelli D, Kuo WT, Estep JA, Louis A, Riccomagno MM, Turner JR, Rao M. The villin1 gene promoter drives cre recombinase expression in extraintestinal tissues. 2020. Cell Mol Gastroenterol Hepatol. 10, 864-867 e865. PMC7573669
PDF PUBMED
He WQ, Wang J, Sheng JY, Zha JM, Graham WV, Turner JR. Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis. 2020. Int J Mol Sci. 21, 993. PMC7037368
PDF PUBMED
Christensen B, Hanauer SB, Gibson PR, Turner JR, Hart J, Rubin DT. Segmental histologic normalisation occurs in ulcerative colitis but does not improve clinical outcomes. 2020. J Crohns Colitis. 14, 1345-1353. PMC7533894
PDF PUBMED
Gillian L Fell, Bennet S Cho, Lorenzo Anez-Bustillos, Duy T Dao, Meredith A Baker, Prathima Nandivada, Alison A O'Loughlin, Alexis P Hurley , Paul D Mitchell, Shawn Rangel, Kathleen M Gura, Mark Puder. Optimizing Duration of Empiric Management of Suspected Central Line-Associated Bloodstream Infections in Pediatric Patients with Intestinal Failure. 2020. The journal of pediatrics. 32687916
Labarta-Bajo L, Nilsen SP, Humphrey G, Schwartz T, Sanders K, Swafford A, Knight R, Turner JR, Zuniga EI. Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection. 2020. J Exp Med. 217, e20192276. PMC7953738
PDF PUBMED
Pongkorpsakol P, Turner JR, Zuo L. Culture of Intestinal Epithelial Cell Monolayers and Their Use in Multiplex Macromolecular Permeability Assays for In Vitro Analysis of Tight Junction Size Selectivity. 2020. Curr Protoc Immunol. 131, e112. PMC8122669
PDF PUBMED
Zuo L, Kuo WT, Turner JR. Tight junctions as targets and effectors of mucosal immune homeostasis. 2020. Cell Mol Gastroenterol Hepatol. 10, 327-340. PMC7326733
PDF PUBMED
Raju P, Shashikanth N, Tsai PY, Pongkorpsakol P, Chanez-Paredes S, Steinhagen PR, Kuo WT, Singh G, Tsukita S, Turner JR. Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice. 2020. J Clin Invest. 130, 5197-5208. PMCID7524482
SUMMARY PDF PUBMED
Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation. 2020. Gastroenterol. 159, 1051-1067. PMC8139320
PDF PUBMED
He WQ, Wang J, Sheng JY, Zha JM, Graham WV, Turner JR. Contributions of myosin light chain kinase to regulation of epithelial paracellular permeability and mucosal homeostasis. 2020. Int J Mol Sci. 21. PMC7037368
PDF PUBMED
Wu S, Yang J, Turner JR. Segmental polyposis. 2020. Gastroenterology. 159, e1-e2
PDF PUBMED
Ong M, Yeruva S, Sailer A, Nilsen SP, Turner JR. Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease. 2020. Lab Invest. 100, 483-490. PMC7047618
PDF PUBMED
Piontek A, Eichner M, Zwanziger D, Beier LS, Protze J, Walther W, Theurer S, Schmid KW, Führer-Sakel D, Piontek J, Krause G.. Targeting claudin-overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin. 2020. Molecular Oncology. 14, 261-276
PUBMED
Xie S, Jiang L, Wang M, Sun W, Yu S, Turner JR, Yu Q. Cadmium ingestion exacerbates Salmonella infection, with a loss of goblet cells through activation of Notch signaling pathways by ROS in the intestine. 2020. J Hazard Mater. 391, 122262
PUBMED
Xie S, Jiang L, Wang M, Sun W, Yu S, Turner JR, Yu Q. Cadmium ingestion exacerbates Salmonella infection, with a loss of goblet cells through activation of Notch signaling pathways by ROS in the intestine. 2020. J Hazard Mater. 391, 122262
PUBMED
Abtahi S, Turner JR. Exploiting Alternative Brush Border Trafficking Routes to Treat Microvillous Inclusion Disease. 2020. Gastroenterol. 159, 1233-1235
PDF PUBMED
Christensen B, Erlich J, Gibson PR, Turner JR, Hart J, Rubin DT. Histologic Healing Is More Strongly Associated with Clinical Outcomes in Ileal Crohn’s Disease than Endoscopic Healing. 2020. Clin Gastroenterol Hepatol. 18, 2518-2525 e2511. PMC7586726
PDF PUBMED
Donowitz M, Turner JR, Verkman AS, Zachos NC. Current and potential future applications of human stem cell models in drug development. 2020. J Clin Invest. 130, 3342-3344. PMC7324189
PDF PUBMED
Cao F, Zhu L, Zhang J, Pongkorpsakol P, Kuo WT, Turner JR, Zhou Q, Wang Y, Chen F, Liu Y, Zuo L. Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment. 2020. Biomed Pharmacother. 131, 110665. PMC8122670
PDF PUBMED
Razmkhah M, Abtahi S, Ghaderi A.. Mesenchymal Stem Cells, Immune Cells and Tumor Cells Crosstalk: A Sinister Triangle in the Tumor Microenvironment. 2019. Curr Stem Cell Res Ther. 14, 43-51. 30112998
PUBMED
Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT, Pan J, Zhou XM, Chen K, Tao M, Odenwald MA, Tamura A, Tsukita S, Turner JR, He WQ. Interleukin 22 expands transit-amplifying cells while depleting Lgr5(+) stem cells via inhibition of wnt and notch signaling. 2019. Cell Mol Gastroenterol Hepatol. 7, 255-274. PMC6352747
PDF PUBMED
Abtahi S, Hakimrabet S, Malekzadeh M, Deghanian AR, Ghaderi A.. Investigating the Levels of Soluble Extracellular Domain of HER2 Protein in the Sera of Meningioma Patients.. 2019. Turk Neurosurg.. 29, 9-13. 29384187
PUBMED
Faghih Z, Abtahi S, Khademi B, Nikfarjam F, Erfani N.. Association of OX40 gene polymorphisms (rs17568G/A and rs229811A/C) with head and neck squamous cell carcinoma. 2019. Mol Biol Rep .. Jun;46(3):2609-2616. 30923998
PUBMED
Gillian L Fell, Lorenzo Anez-Bustillos, Duy T Dao, Meredith A Baker, Prathima Nandivada, Bennet S Cho, Amy Pan, Alison A O'Loughlin, Vania Nose, Kathleen M Gura, Mark Puder. Alpha-tocopherol in intravenous lipid emulsions imparts hepatic protection in a murine model of hepatosteatosis induced by the enteral administration of a parenteral nutrition solution. 2019. PLoS One. 14(7). 6622470
Meredith A Baker, Prathima Nandivada, Paul D Mitchell, Gillian L Fell, Amy Pan, Bennet S Cho, Denis J De La Flor, Lorenzo Anez-Bustillos, Duy T Dao, Vania Nosé, Mark Puder. Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling. 2019. Journal of pediatric surgery. 54(11), 2392-97. 6790164
Gillian L Fell , Bennet S Cho, Duy T Dao, Lorenzo Anez-Bustillos, Meredith A Baker, Prathima Nandivada, Amy Pan, Alison A O'Loughlin, Paul D Mitchell, Vania Nose, Kathleen M Gura, Mark Puder. Fish oil protects the liver from parenteral nutrition-induced injury via GPR120-mediated PPARγ signaling. 2019. Prostaglandins, leukotrienes, and fatty acids. 143, 8-14. 6642797
Sarah J Carlson, Alison A O'Loughlin, Lorenzo Anez-Bustillos, Meredith A Baker, Nicholas A Andrews, Georgia Gunner, Duy T Dao, Amy Pan, Prathima Nandivada, Melissa Chang , Eileen Cowan , Paul D Mitchell, Kathleen M Gura, Michela Fagiolini, Mark Puder. A Diet With Docosahexaenoic and Arachidonic Acids as the Sole Source of Polyunsaturated Fatty Acids Is Sufficient to Support Visual, Cognitive, Motor, and Social Development in Mice. 2019. Frontiers in neuroscience. 13, 72. 6397844
Lorenzo Anez-Bustillos, Eileen Cowan, Maria B Cubria, Juan C Villa-Camacho, Amin Mohamadi, Duy T Dao, Amy Pan, Gillian L Fell, Meredith A Baker, Prathima Nandivada, Ara Nazarian, Mark Puder. Effects of dietary omega-3 fatty acids on bones of healthy mice. 2019. Clinical nutrition. 38(5), 2145-54. 6465171
Tse CM, Yin J, Singh V, Sarker R, Lin R, Verkman AS, Turner JR, Donowitz M. cAMP stimulates SLC26A3 activity in human colon by a CFTR-dependent mechanism that does not require CFTR activity. 2019. Cell Mol Gastroenterol Hepatol. 7, 641-653. PMC6438990
PDF PUBMED
Turner JR. Rigor, reproducibility, and responsibility: a quantum of solace. 2019. Cell Mol Gastroenterol Hepatol. 7, 869-871. PMC6522661
PDF PUBMED
Turner JR. On the genesis of CMGH. 2019. Cell Mol Gastroenterol Hepatol. 8, 143-144. PMC6599096
PDF PUBMED
Christensen B, Hanauer SB, Erlich J, Kassim O, Gibson PR, Turner JR, Hart J, Rubin DT. Histologic healing is more strongly associated with clinical outcomes in ileal Crohn’s disease than endoscopic healing. 2019. Clin Gastroenterol Hepatol
PDF PUBMED
Pandey SP, Yan J, Turner JR, Abraham C. Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. 2019. Mucosal Immunol. 12, 874-887. PMC6688861
PDF PUBMED
Nalle SC, Zuo L, Ong M, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. 2019. J Clin Invest. 129, 902-914. PMC6355225
SUMMARY PDF PUBMED
Cil O, Anderson MO, Yen R, Kelleher B, Huynh TL, Seo Y, Nilsen SP, Turner JR, Verkman AS. Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A. 2019. FASEB J. 33, 11247-11257. PMC6766656
PDF PUBMED
Ishigaki S, Kuwae M, Ishii M, Asakura T, Ueda S, Betsuyaku T.. Black pleural effusion caused by pancreatic pseudocyst rupture.. 2019. Clin Case Rep.. 7, 385-386
Kuo WT, Shen L, Zuo L, Shashikanth N, Ong M, Wu L, Zha J, Edelblum KL, Wang Y, Wang Y, Nilsen SP, Turner JR. Inflammation-induced occludin downregulation limits epithelial apoptosis by suppressing caspase-3 expression. 2019. Gastroenterology. 157, 1323-1337. PMC6815722
SUMMARY PDF PUBMED
Karla F Castro-Ochoa, Hilda Vargas-Robles, Sandra Chánez-Paredes, Alfonso Felipe-López, Rodolfo I Cabrera-Silva, Mineko Shibayama, Abigail Betanzos, Porfirio Nava, Erwin A Galinski, Michael Schnoor. Homoectoine Protects Against Colitis by Preventing a Claudin Switch in Epithelial Tight Junctions. 2019. Digestive Diseases and Sciences. 64, 409–420. 30269272
PUBMED
Serrano C, Galán S, Rubio JF, Candelario-Martínez A, Montes-Gómez AE, Chánez-Paredes S, Cedillo-Barrón L, Schnoor M, Meraz-Ríos MA, Villegas-Sepúlveda N, Ortiz-Navarrete V, Nava P. Compartmentalized Response of IL-6/STAT3 Signaling in the Colonic Mucosa Mediates Colitis Development. 2019. The Journal of Immunology. 202, 1239-1249. 30626693
PUBMED
Chánez-Paredes S, Montoya-García A, Schnoor M. Cellular and pathophysiological consequences of Arp2/3 complex inhibition: role of inhibitory proteins and pharmacological compounds. 2019. Cellular and Molecular Life Sciences. 76, 3349–3361. 31073744
PUBMED
Eduardo Vadillo, Sandra Chánez-Paredes, Hilda Vargas-Robles, Idaira María Guerrero-Fonseca, Ramón Castellanos-Martínez, Alexander García-Ponce, Porfirio Nava, Daniel Alberto Girón-Pérez, Leopoldo Santos-Argumedo, Michael Schnoor. Intermittent rolling is a defect of the extravasation cascade caused by Myosin1e-deficiency in neutrophils. 2019. Proc Natl Acad Sci USA. 116, 26752–26758. PMC6936681
PUBMED
Graham WV, He W, Marchiando AM, Zha J, Singh G, Li HS, Biswas A, Ong M, Jiang ZH, Choi W, Zuccola H, Wang Y, Griffith J, Wu J, Rosenberg HJ, Wang Y, Snapper SB, Ostrov D, Meredith SC, Miller LW, Turner JR. Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. 2019. Nat Med. 25, 690-700. PMC6461392
SUMMARY PDF PUBMED
Escudero P, Yeste J, Pascual-Izarra C, Villa R, Alvarez M. Color tunable pressure sensors based on polymer nanostructured membranes for optofluidic applications. 2019. Scientific Reports. 9, 3259. PMC6397196
PUBMED
Hugot J-P, Al Nabhani Z, Berrebi D, Martinez-Vinson C, Montcuquet N, Dietrich G, Singh G, Turner JR, Madre C, Roy M, Ogier-Denis E, Dussaillant M, Cerf-Bensussan N, Zouali H, Jung C, Daniel F, Barreau F. Nod2 protects 1 remote small intestinal sites in case of colonic inflammation. 2019. BioRxiv
PDF
Richter JF, Hildner M, Schmauder R, Turner JR, Schumann M, Reiche J. Occludin knockdown is not sufficient to induce transepithelial macromolecule passage. 2019. Tissue Barriers. 7, 1612661. PMC6619991
PDF PUBMED
Beier LS, Rossa J, Woodhouse S, Bergmann S, Kramer HB, Protze J, Eichner M, Piontek A, Vidal-Y-Sy S, Brandner JM, Krause G, Zitzmann N, Piontek J.. Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells. 2019. International Journal of Molecular Sciences. 20
PUBMED
Buckley A, Turner JR. Cell Biology of Tight Junction Barrier Regulation and Mucosal Disease. 2018. Cold Spring Harb Perspect Biol. 10. PMC5749156
PDF PUBMED
Turner JR, Goldenring JR, Rescigno M, Wells RG. State of the journal: CMGH’s progress, prospects, and impact factor. 2018. Gastroenterology. 154, 460-461
PDF PUBMED
Yeste J, Illa X, Alvarez M, Villa R. Engineering and monitoring cellular barrier models. 2018. Journal of Biological Engineering. 12, 18. PMC6134550
PUBMED
Acarregui A, Ciriza J, Saenz del Burgo L, Gurruchaga Iribar L, Yeste J, Illa X, Orive G, Hernández RM, Villa R, Pedraz JL. Characterization of an Encapsulated Insulin Secreting Human Pancreatic Beta Cell Line in a Modular Microfluidic Device. 2018. Journal of Drug Targeting. 26, 36-44
PUBMED
Yeste J, Martínez-Gimeno L, Illa X, Laborda P, Guimerà A, Sánchez-Marín JP, Villa R, Giménez I. A perfusion chamber for monitoring transepithelial NaCl transport in an in vitro model of the renal tubule. 2018. Biotechnology and bioengineering. 115, 1604-1613
PUBMED
Hou Q, Ye L, Liu H, Huang L, Yang Q, Turner JR, Yu Q. Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22. 2018. Cell Death Differ. 25, 1657-1670. PMC6143595
PDF PUBMED
Odenwald MA, Choi W, Kuo WT, Singh G, Sailer A, Wang Y, Shen L, Fanning AS, Turner JR. The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo. 2018. J Biol Chem. 293, 17317-17335. PMC6231134
SUMMARY PDF PUBMED
Kristina Schaedlich, Scarlett Gebauer, Luise Hunger, Laura-Sophie Beier, Holger M Koch, Martin Wabitsch, Bernd Fischer, Jana Ernst. DEHP deregulates adipokine levels and impairs fatty acid storage in human SGBS-adipocytes. 2018. Scientific Reports. 8
PUBMED
Syed S, Yeruva S, Herrmann J, Sailer A, Sadiq K, Iqbal N, Kabir F, Ahmed K, Qureshi S, Moore SR, Turner J, Ali SA. Environmental enteropathy in undernourished Pakistani children: clinical and histomorphometric analyses. 2018. Am J Trop Med Hyg. 98, 1577-1584. PMC6086170
PDF PUBMED
Hu MD, Ethridge AD, Lipstein R, Kumar S, Wang Y, Jabri B, Turner JR, Edelblum KL. Epithelial IL-15 Is a Critical Regulator of gammadelta Intraepithelial Lymphocyte Motility within the Intestinal Mucosa. 2018. J Immunol. 201, 747-756. PMC6075741
PDF PUBMED
Enkai Li, Hu Liu, Yakui Li, Ling Liu, Fenglai Wang, Defa Li, Shuai Zhang. Determination of net energy content of dietary lipids fed to growing pigs using indirect calorimetry. 2018. Journal of Animal Science. 96, 2184-2194
PUBMED
Hoffman JM, Sideri A, Ruiz JJ, Stavrakis D, Shih DQ, Turner JR, Pothoulakis C, Karagiannides I. Mesenteric adipose-derived stromal cells from Crohn’s disease patients induce protective effects in colonic epithelial cells and mice with colitis. 2018. Cell Mol Gastroenterol Hepatol. 6, 1-16. PMC6008259
PDF PUBMED
Sallis BF, Erkert L, Monino-Romero S, Acar U, Wu R, Konnikova L, Lexmond WS, Hamilton MJ, Dunn WA, Szepfalusi Z, Vanderhoof JA, Snapper SB, Turner JR, Goldsmith JD, Spencer LA, Nurko S, Fiebiger E. An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning. 2018. J Allergy Clin Immunol. 141, 1354-1364 e1359. PMC6425755
PDF PUBMED
Steinhangen PR, . Effectiveness and Safety of Vedolizumab in Anti-TNF-Naïve Patients With Inflammatory Bowel Disease-A Multicenter Retrospective European Study. 2018. Inflammatory Bowel Diseases. 29788318
Garber JJ, Mallick EM, Scanlon KM, Turner JR, Donnenberg MS, Leong JM, Snapper SB. Attaching-and-effacing pathogens exploit junction regulatory activities of N-WASP and SNX9 to disrupt the intestinal barrier. 2018. Cell Mol Gastroenterol Hepatol. 5, 273-288. PMC5904039
PDF PUBMED
Aihara E, Medina-Candelaria NM, Hanyu H, Matthis AL, Engevik KA, Gurniak CB, Witke W, Turner JR, Zhang T, Montrose MH. Cell injury triggers actin polymerization to initiate epithelial restitution. 2018. J Cell Sci. 131. PMC6127731
PDF PUBMED
Zukauskas A, Mrsny RJ, Cortes Barrantes P, Turner JR, Leong JM, McCormick BA. Transporters MRP1 and MRP2 regulate opposing inflammatory signals to control transepithelial neutrophil migration during streptococcus pneumoniae lung infection. 2018. mSphere. 3. PMC6034076
PDF PUBMED
Almansour K, Taverner A, Turner JR, Eggleston IM, Mrsny RJ. An intestinal paracellular pathway biased toward positively-charged macromolecules. 2018. J Control Release. 288, 111-125. PMC6219475
PDF PUBMED
Do Hyung Kim, Tiaosi Xing, Zhibin Yang, Ronald Dudek, Qun Lu, Yan-Hua Chen. Epithelial mesenchymal transition in embryonic development, tissue repair and cancer: a comprehensive overview. 2018. Journal of clinical medicine. 7 (1), 1. PMC5791009
PUBMED
Ghahartars M, Najafzadeh S, Abtahi S, Fattahi MJ, Ghaderi A.. Investigation of Interleukin-27 in the Sera of Nonmelanoma Skin Cancer Patients. 2018. Dermatol Res Pract. 30581461
PUBMED
Tiaosi Xing, Daniel T Hass, Samuel S Zhang, Colin J Barnstable. The 3-Phosphoinositide-Dependent Protein Kinase 1 Inhibits Rod Photoreceptor Development. 2018. Frontiers in cell and developmental biology. 6, 134. PMC6191476
PUBMED
Abtahi S, Izadi Jahromi F, Dabbaghmanesh MH, Malekzadeh M, Ghaderi A.. Association between CTLA-4 + 49A > G and – 318C > T single-nucleotide polymorphisms and susceptibility to thyroid neoplasm. 2018. Endocrine. 30078171
PUBMED
Ghaderi, A. Abtahi, S.. Mesenchymal Stem Cells: Miraculous Healers or Dormant Killers?. 2018. Stem Cell Rev Rep. 14, 722-733. 29799101
PUBMED
Tiaosi Xing, Rolando Camacho Salazar, Yan-Hua Chen. Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer. 2018. Tissue Barriers. 5 (4), e1356901. PMC5788446
PUBMED
Krugliak Cleveland N, Huo D, Sadiq F, Sofia MA, Marks J, Cohen RD, Hanauer SB, Turner J, Hart J, Rubin DT. Assessment of peri-polyp biopsy specimens of flat mucosa in patients with inflammatory bowel disease. 2018. Gastrointest Endosc. 87, 1304-1309
PDF PUBMED
Turner JR, Krug SM. Tricellulin is regulated via interleukin-13-receptor alpha2, affects macromolecule uptake, and is decreased in ulcerative colitis. 2018. Mucosal Immunol. 11, 345-356. PMC5730503
PDF PUBMED
Abtahi, S. Malekzadeh, M. Nikravan, G. Ghaderi, A.. Measurement of Lung Cancer Tumor Markers in a Glass Wool Company Workers Exposed to Respirable Synthetic Vitreous Fiber and Dust. 2018. Int J Occup Environ Med. 9, 23-31. PMC6466973
PUBMED
Yeste, J., M. García-Ramírez, X. Illa, A. Guimerà, C. Hernández, R. Simó, R. Villa. A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood–retinal barrier. 2018. Lab on a Chip. 18, 95-105
PUBMED
Duy T Dao, Lorenzo Anez-Bustillos, Amy Pan, Alison A O'Loughlin, Paul D Mitchell, Gillian L Fell, Meredith A Baker, Bennet S Cho, Prathima Nandivada, Arthur P Nedder, Charles J Smithers, Nancy Chen, Robert Comeau, Kevin Holmes, Susan Kalled , Angela Norton, Bohong Zhang, Mark Puder. Vascular Endothelial Growth Factor Enhances Compensatory Lung Growth in Piglets. 2018. Surgery. 164(6), 1279-86. 6446901
Duy T Dao, Prathima Nandivada, Jacqueline T Vuong, Lorenzo Anez-Bustillos, Amy Pan, Hiroko Kishikawa, Paul D Mitchell, Meredith A Baker, Gillian L Fell, Thomas Martin, Mark Puder. Vascular endothelial growth factor accelerates compensatory lung growth by increasing the alveolar units. 2018. Pediatric research. 83(6), 1182-9. 6019135
Meredith A Baker, Prathima Nandivada, Paul D Mitchell, Gillian L Fell, Amy Pan, Lorenzo Anez-Bustillos, Duy T Dao, Kathleen M Gura, Vania Nosé, Mark Puder. Pretreatment with intravenous fish oil reduces hepatic ischemia reperfusion injury in a murine model. 2018. Surgery. 163(5), 1035-9. 5936675
Prathima Nandivada, Gillian L Fell, Amy H Pan, Vania Nose, Paul D Mitchell, Kathleen M Gura, Mark Puder. Parenteral Soybean Oil Induces Hepatosteatosis Despite Addition of Fish Oil in a Mouse Model of Intestinal Failure-Associated Liver Disease. 2018. Journal of parenteral and enteral nutrition. 42(2), 403-11. 29187040
Drolia R, Tenguria S, Durkes AC, Turner JR, Bhunia AK. Listeria adhesion protein induces intestinal epithelial barrier dysfunction for bacterial translocation. 2018. Cell Host Microbe. 23, 470-484 e477. PMC6750208
PDF PUBMED
Weber CR, Turner JR. Dynamic modeling of the tight junction pore pathway. 2017. Ann N Y Acad Sci. 1397, 209-218. PMC5488723
PDF PUBMED
Wu RL, Vazquez-Roque MI, Carlson P, Burton D, Grover M, Camilleri M, Turner JR. Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression. 2017. Lab Invest. 97, 14-23. PMC5215009
PDF PUBMED
Amadi B, Besa E, Zyambo K, Kaonga P, Louis-Auguste J, Chandwe K, Tarr PI, Denno DM, Nataro JP, Faubion W, Sailer A, Yeruva S, Brantner T, Murray J, Prendergast AJ, Turner JR, Kelly P. Impaired barrier function and autoantibody generation in malnutrition enteropathy in Zambia. 2017. EBioMedicine. 22, 191-199. PMC5552244
PDF PUBMED
Peters SA, Edogawa S, Sundt WJ, Dyer RB, Dalenberg DA, Mazzone A, Singh RJ, Moses N, Smyrk TC, Weber C, Linden DR, MacNaughton WK, Turner JR, Camilleri M, Katzka DA, Farrugia G, Grover M. Constipation-predominant irritable bowel syndrome females have normal colonic barrier and secretory function. 2017. Am J Gastroenterol. 112, 913-923. PMC5502210
PDF PUBMED
Shashikanth N, Yeruva S, Ong M, Odenwald MA, Pavlyuk R, Turner JR. Epithelial organization: the gut and beyond. 2017. Compr Physiol. 7, 1497-1518
PDF PUBMED
Tsai PY, Zhang B, He WQ, Zha JM, Odenwald MA, Singh G, Tamura A, Shen L, Sailer A, Yeruva S, Kuo WT, Fu YX, Tsukita S, Turner JR. IL-22 upregulates epithelial claudin-2 to drive diarrhea and enteric pathogen clearance. 2017. Cell Host Microbe. 21, 671-681 e674. PMC5541253
SUMMARY PDF PUBMED
Blackwood BP, Wood DR, Yuan C, Nicolas J, De Plaen IG, Farrow KN, Chou P, Turner JR, Hunter CJ. A role for cAMP and protein kinase A in experimental necrotizing enterocolitis. 2017. Am J Pathol. 187, 401-417. PMC5389366
PDF PUBMED
Odenwald MA, Choi W, Buckley A, Shashikanth N, Joseph NE, Wang Y, Warren MH, Buschmann MM, Pavlyuk R, Hildebrand J, Margolis B, Fanning AS, Turner JR. ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. 2017. J Cell Sci. 130, 243-259. PMC5394778
PDF PUBMED
Odenwald MA, Turner JR. The intestinal epithelial barrier: a therapeutic target?. 2017. Nat Rev Gastroenterol Hepatol. 14, 9-21. PMC5554468
PDF PUBMED
Wang LC, Yu Q, Edwards V, Lin B, Qiu J, Turner JR, Stein DC, Song W. Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation. 2017. PLoS Pathog. 13, e1006269. PMC5391109
PDF PUBMED
Ma Y, Yue J, Zhang Y, Shi C, Odenwald M, Liang WG, Wei Q, Goel A, Gou X, Zhang J, Chen SY, Tang WJ, Turner JR, Yang F, Liang H, Qin H, Wu X. ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics. 2017. Nat Commun. 1, 15375. PMC5458510
PDF PUBMED
Choi W, Yeruva S, Turner JR. Contributions of intestinal epithelial barriers to health and disease. 2017. Exp Cell Res. 358, 71-77. PMC5958612
PDF PUBMED
Edelblum KL, Sharon G, Singh G, Odenwald MA, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian SK, Turner JR. The microbiome activates CD4 T-cell-mediated immunity to compensate for increased intestinal permeability. 2017. Cell Mol Gastroenterol Hepatol. 4, 285-297. PMC5540699
PDF PUBMED
Christensen B, Hanauer SB, Erlich J, Kassim O, Gibson PR, Turner JR, Hart J, Rubin DT. Histologic normalization occurs in ulcerative colitis and is associated with improved clinical outcomes. 2017. Clin Gastroenterol Hepatol. 15, 1557-1564 e1551. PMC5618439
PDF PUBMED
Turner JR. The CMGH awards. 2017. Cell Mol Gastroenterol Hepatol. 3, 129-130. PMC5331835
PDF PUBMED
Turner JR. A picture is worth a thousand words. 2017. Cell Mol Gastroenterol Hepatol. 3, 1. PMC5247416
PDF PUBMED
France M, Turner JR. The mucosal barrier at a glance. 2017. J Cell Sci. 130, 307-314. PMC5278669
PDF PUBMED
Shashikanth N, Kisting MA, Leckband DE. Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions. 2017. Scientific Reports. 7:41469. PMC4806357
PUBMED
Shi-xue Dai, Hong-xiang Gu, Qian-yi Lin, Yan-kun Wu, Xiao-yan Wang, Shao-zhuo Huang, Tiao-si Xing, Min-hua Chen, Qing-fang Zhang, Zhong-wen Zheng, Wei-hong Sha. Decreased CD8+ CD28+/CD8+ CD28–T cell ratio can sensitively predict poor outcome for patients with complicated Crohn disease. 2017. Medicine. 96(26)
PUBMED
Abtahi, S. Davani, F. Mojtahedi, Z. Hosseini, S. V. Bananzadeh, A. Ghaderi, A.. Dual association of serum interleukin-10 levels with colorectal cancer. 2017. J Cancer Res Ther. 13, 252-256
PUBMED
Duy T Dao, Lorenzo Anez-Bustillos, Alison A O'Loughlin, Amy Pan , Arthur P Nedder , Dana Bolgen, Charles Jason Smithers, Jill Zalieckas, Craig W Lillehei, Prathima Nandivada, Meredith A Baker, Gillian L Fell, Bennet S Cho, Mark Puder. Technique and perioperative management of left pneumonectomy in neonatal piglets. 2017. Journal of surgical research. 212, 146-52. 5839113
S Dai, H Gu, Q Lin, Y Wu, X Wang, S Huang, T Xing, M Chen, Q Zhang. CD8+ CD28+/CD8+ CD28− T cell equilibrium can predict the active stage for patients with inflammatory bowel disease. 2017. Clinics and Research in Hepatology and Gastroenterology. 41 (6), 693-702
PUBMED
Steinhagen PR. Fundamentals of the microbiome. 2017. Der Internist
Prathima Nandivada, Gillian L Fell, Paul D Mitchell, Alexis K Potemkin, Alison A O'Loughlin, Kathleen M Gura, Mark Puder. Long-Term Fish Oil Lipid Emulsion Use in Children With Intestinal Failure-Associated Liver Disease. 2017. Journal of parenteral and enteral nutrition. 41(6), 930-937. 26962059
Prathima Nandivada, Lorenzo Anez-Bustillos, Alison A O'Loughlin, Paul D Mitchell, Meredith A Baker, Duy T Dao, Gillian L Fell, Alexis K Potemkin, Kathleen M Gura, Ellis J Neufeld, Mark Puder. Risk of post-procedural bleeding in children on intravenous fish oil. 2017. American journal of surgery. 4(4), 733-37. 5464992
Gillian L Fell, Bennet S Cho, Amy Pan, Vania Nose, Lorenzo Anez-Bustillos, Duy T Dao, Meredith A Baker, Prathima Nandivada, Kathleen M Gura, Mark Puder. A Comparison of Fish Oil Sources for Parenteral Lipid Emulsions in a Murine Model. 2017. Journal of parenteral and enteral nutrition. 41(2), 181-87. 26993989
Yin Zhou, Wenqiong Xin, Guozhu Yang, Shuguang Jin, Lin Zhong, Yuan Li. Annular Pancreas Combined with Intestinal Malrotation and Duodenal Duplication: A Rare Case of Multiple Alimentary Tract Anomalies in a Preadolescent.. 2017. Journal of Paediatrics and Child Health. Oct;53(10), 1032-1034. PMID: 28975755
PUBMED
S Dai, H Gu, Q Lin, T Xing, M Chen, T Zhong, G Wu, Y Feng, H Liu, Y Gao. Disequilibrium in the CD8+CD28+/CD8+CD28− T Lymphocyte Balance Is Related to Prognosis in Rats with Trinitrobenzenesulfonic Acid-Induced Colitis. 2017. Digestive diseases and sciences. 62 (3), 639-651
PUBMED
Yin Zhou, Yibo Li, Bin Zhou, Keling Chen, Zhaoying Lyv, Dongmei Huang, Bin Li, Zhicheng Xu, Bo Xiang, Shuguang Jin, Xiaofeng Sun, Yuan Li. Inflammation and Apoptosis: Dual Mediator Role for Toll-like Receptor 4 in the Development of Necrotizing Enterocolitis. 2017. Inflammatory Bowel Diseases. Jan;23(1), 44-56. 27849634
PUBMED
Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM, Jr., Turner JR. Not all mice are the same: Standardization of animal research data presentation. 2016. Gastroenterology. 150, 1503-1504
PDF PUBMED
Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM, Jr., Turner JR. Not all mice are the same: Standardization of animal research data presentation. 2016. Hepatology. 63, 1752-1754
PDF PUBMED
Cai Y, Shashikanth N, Leckband DE, Schwartz DK. Cadherin Diffusion in Supported Lipid Bilayers Exhibits Calcium-Dependent Dynamic Heterogeneity. 2016. Biophysical Journal. 111 (12), 2658–2665. PMC5192687
PUBMED
Alexander García Ponce, Alí F Citalán Madrid, Hilda Vargas Robles , Sandra Chánez Paredes, Porfirio Nava, Abigail Betanzos, Alexander Zarbock, Klemens Rottner, Dietmar Vestweber, Michael Schnoor. Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility. 2016. Sci Rep .. 6. 29003
PUBMED
Faraji, A. Abtahi, S. Ghaderi, A. Samsami Dehaghani, A.. Transforming Growth Factor beta1 (TGF-beta1) in the Sera of Postmenopausal Osteoporotic Females. 2016. Int J Endocrinol Metab. 14, e36511
PUBMED
Prathima Nandivada, Meredith A Baker, Paul D Mitchell, Alison A O'Loughlin, Alexis K Potemkin, Lorenzo Anez-Bustillos, Sarah J Carlson, Duy T Dao, Gillian L Fell, Kathleen M Gura, Mark Puder. Predictors of failure of fish-oil therapy for intestinal failure-associated liver disease in children. 2016. American journal of clinical nutrition. 104(3), 663-70. 4997303
Turner JR. Taiwan: A CMGH champion!. 2016. Cell Mol Gastroenterol Hepatol. 2, 2. PMC4980718
PDF PUBMED
Alexander García-Ponce, Sandra Chánez Paredes, Karla Fabiola Castro Ochoa, Michael Schnoor. Regulation of endothelial and epithelial barrier functions by peptide hormones of the adrenomedullin family. 2016. Tissue Barriers. 4. PMC5214765
PUBMED
Mir H, Meena AS, Chaudhry KK, Shukla PK, Gangwar R, Manda B, Padala MK, Shen L, Turner JR, Dietrich P, Dragatsis I, Rao R. Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice. 2016. Biochim Biophys Acta. 1860, 765-774. PMC4776745
PDF PUBMED
Turner JR. Cryptosporidium priming is more effective than vaccine for protection against Cryptosporidiosis in a murine protein malnutrition model. 2016. PLoS Negl Trop Dis. 10, e0004820. PMC4965189
PDF PUBMED
Gillian L Fell, Alison A O'Loughlin, Prathima Nandivada, Alexis K Potemkin, Paul D Mitchell, Judith Mahoney, Kathleen M Gura, Mark Puder. Methods to Reduce Medication Errors in a Clinical Trial of an Investigational Parenteral Medication. 2016. Contemporary clinical trials communications. 4, 64-67. 4967555
Turner JR. Looking back; looking forward!. 2016. Cell Mol Gastroenterol Hepatol. 2, 1. PMC4980711
PDF PUBMED
Turner JR. PubMed, PubMed Central, and impact factor. 2016. Cell Mol Gastroenterol Hepatol. 2, 537. PMC5042885
PDF PUBMED
Prathima Nandivada, Gillian L Fell, Amy H Pan, Vania Nose, Pei-Ra Ling, Bruce R Bistrian, Mark Puder. Eucaloric Ketogenic Diet Reduces Hypoglycemia and Inflammation in Mice with Endotoxemia. 2016. Lipids. 51(6), 703-14. 27117864
Yeste, J., X. Illa, C. Gutiérrez, M. Solé, A. Guimerà, R. Villa. Geometric correction factor for transepithelial electrical resistance measurements in transwell and microfluidic cell cultures. 2016. Journal of Physics D: Applied Physics. 49, 375401
PUBMED
Turner JR, Lingen MW. The oral cavity and gastrointestinal tract. 2016. Basic Pathology. 10th Ed
Prathima Nandivada, Gillian L Fell, Kathleen M Gura, Mark Puder. Lipid emulsions in the treatment and prevention of parenteral nutrition-associated liver disease in infants and children. 2016. American journal of clinical nutrition. 103(2), 629-34. 26791189
Choi VM, Herrou J, Hecht AL, Teoh WP, Turner JR, Crosson S, Bubeck Wardenburg J. Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice. 2016. Nat Med. 22, 563-567. PMC4860040
PDF PUBMED
Herrmann JR, Turner JR. Beyond Ussing’s chambers: contemporary thoughts on integration of transepithelial transport. 2016. Am J Physiol Cell Physiol. 310, C423-431. PMC4796286
PDF PUBMED
Turner JR. Epithelia and gastrointestinal function. 2016. Yamada’s Textbook of Gastroenterology. 6th Ed, 317-329
PDF
Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM, Jr., Turner JR. Not all mice are the same: standardization of animal research data presentation. 2016. Cell Mol Gastroenterol Hepatol. 2, 391-393. PMC5042602
PDF PUBMED
Melissa I Chang, Sarah J Carlson, Prathima Nandivada, Alison A O'Loughlin, Alexis K Potemkin, Eileen Cowan, Paul D Mitchell, Kathleen M Gura, Mark Puder. Challenging the 48-Hour Rule-Out for Central Line-Associated Bloodstream Infections in the Pediatric Intestinal Failure Population: A Retrospective Pilot Study. 2016. Journal of parenteral and enteral nutrition. 40(4), 567-73. 25567785
Ronaghan NJ, Shang J, Iablokov V, Zaheer R, Colarusso P, Dion S, Desilets A, Leduc R, Turner JR, MacNaughton WK. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. 2016. Am J Physiol Gastrointest Liver Physiol. 311, G466-479. PMC5076006
PDF PUBMED
Prathima Nandivada, Gillian L Fell, Kathleen M Gura, Mark Puder. Lipid emulsions in the treatment and prevention of parenteral nutrition-associated liver disease in infants and children. 2016. American journal of clinical nutrition. 103(2), 629-34. 26791189
Nalle SC, Turner JR. Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. 2015. Mucosal Immunol. 8, 720-730
PDF PUBMED
Weber CR, Liang GH, Wang Y, Das S, Shen L, Yu AS, Nelson DJ, Turner JR. Claudin-2-dependent paracellular channels are dynamically gated. 2015. Elife. 4, e09906. PMC4755754
PDF PUBMED
Brian T Kalish, Gillian L Fell, Prathima Nandivada, Mark Puder. Clinically Relevant Mechanisms of Lipid Synthesis, Transport, and Storage. 2015. Journal of parenteral and enteral nutrition. 39, 8-17. 26187937
Turner JR. A journey of a thousand miles begins with a single step, and then another. 2015. Cell Mol Gastroenterol Hepatol. 1, 121-122. PMC5301140
PDF PUBMED
Tripathi AK, Haldar S, Qian J, Beserra A, Suda S, Singh A, Hopfer U, Chen SG, Garrick MD, Turner JR, Knutson MD, Singh N. Prion protein functions as a ferrireductase partner for ZIP14 and DMT1. 2015. Free Radic Biol Med. 84, 322-330. PMC4476631
PDF PUBMED
Prathima Nandivada, Melissa I Chang, Alexis K Potemkin, Sarah J Carlson, Eileen Cowan, Alison A Oʼloughlin, Paul D Mitchell, Kathleen M Gura, Mark Puder. The natural history of cirrhosis from parenteral nutrition-associated liver disease after resolution of cholestasis with parenteral fish oil therapy. 2015. Annals of Surgery. 261(1), 172-9. 24374535
Luther J, Garber JJ, Khalili H, Dave M, Bale SS, Jindal R, Motola DL, Luther S, Bohr S, Jeoung SW, Deshpande V, Singh G, Turner JR, Yarmush ML, Chung RT, Patel SJ. Hepatic injury in nonalcoholic steatohepatitis contributes to altered intestinal permeability. 2015. Cell Mol Gastroenterol Hepatol. 1, 222-232. PMC4578658
PDF PUBMED
Prathima Nandivada, Alexis K Potemkin, Sarah J Carlson, Melissa I Chang, Eileen Cowan, Alison A O'Loughlin, Kathleen M Gura, Mark Puder. Elevated Alkaline Phosphatase in Infants With Parenteral Nutrition-Associated Liver Disease Reflects Bone Rather Than Liver Disease. 2015. Journal of parenteral and enteral nutrition. 39(8), 973-6. 25106918
Lingaraju A, Long TM, Wang Y, Austin JR, 2nd, Turner JR. Conceptual barriers to understanding physical barriers. 2015. Semin Cell Dev Biol. 42, 13-21. PMC4562871
PDF PUBMED
Turner JR. CMGH Is growing!. 2015. Cell Mol Gastroenterol Hepatol. 1, 453. PMC5301405
PDF PUBMED
Dubnansky EC, Lowe CB, Petrovic TK, Brounstein LM, El-Serag HB, Turner JR, Omary MB. Why send your paper to Gastroenterology: global outreach and partnerships with sister journals, CGH and CMGH, among a menu of offerings. 2015. Gastroenterology. 148, 673-678
PDF PUBMED
Turner JR, Odze RD. Polyps of the Stomach. 2015. Odze and Goldblum Surgical Pathology of the Gastrointestinal Tract, Liver, Biliary Tract and Pancreas. 3rd Ed, 540-578
PDF
Chen P, Starkel P, Turner JR, Ho SB, Schnabl B. Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice. 2015. Hepatology. 61, 883-894. PMC4340725
PDF PUBMED
Turner JR, Goldenring JR, Wells RG, Brounstein LM. CMGH: the revolution starts now. 2015. Cell Mol Gastroenterol Hepatol. 1, 1. PMC5301188
PDF PUBMED
Sarah J Carlson, Prathima Nandivada, Melissa I Chang, Paul D Mitchell, Alison O'Loughlin, Eileen Cowan, Kathleen M Gura, Vania Nose, Bruce R Bistrian, Mark Puder. The addition of medium-chain triglycerides to a purified fish oil-based diet alters inflammatory profiles in mice. 2015. Metabolism. 64(2), 274-82. 25458829
Shashikanth N, Petrova YI, Park S, Chekan J, Maiden S, Spano S, Ha T, Gumbiner BM, Leckband DE. Allosteric regulation of E-cadherin adhesion. 2015. Journal of Biological Chemistry. 290 (35), 21749-21761. PMC4571897
PUBMED
Gillian L Fell, Prathima Nandivada, Kathleen M Gura, Mark Puder. Intravenous Lipid Emulsions in Parenteral Nutrition. 2015. Advances in nutrition. 6(5), 600-10. 26374182
Pan J, Zhang L, Odenwald MA, Shen L, Turner JR, Bergelson JM. Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. 2015. J Virol. 89, 4311-4318. PMC4442383
PDF PUBMED
Edelblum KL, Turner JR. Epithelial cells: structure, transport, and barrier function. 2015. Mucosal Immunology. 4th Ed, 187-210
PDF
Carolina Pinzon-Guzman, Tiaosi Xing, Samuel Shao-Min Zhang, Colin J Barnstable. Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase. 2015. Journal of Molecular Neuroscience. 55(1), 152-159
PUBMED
Yin Zhou, Jiaywei Tsauo, Yuan Li, Xiao Li. Selective Embolization of Systemic Collaterals for the Treatment of Recurrent Hemoptysis Secondary to the Unilateral Absence of a Pulmonary Artery in a Child. 2015. CardioVascular and Interventional Radiology. Oct;38(5), 1312-1315. PMID: 25145922
PUBMED
Sideri A, Bakirtzi K, Shih DQ, Koon HW, Fleshner P, Arsenescu R, Arsenescu V, Turner JR, Karagiannides I, Pothoulakis C. Substance P mediates pro-inflammatory cytokine release form mesenteric adipocytes in inflammatory bowel disease patients. 2015. Cell Mol Gastroenterol Hepatol. 1, 420-432. PMC4629258
PDF PUBMED
Setty M, Discepolo V, Abadie V, Kamhawi S, Mayassi T, Kent A, Ciszewski C, Maglio M, Kistner E, Bhagat G, Semrad C, Kupfer SS, Green PH, Guandalini S, Troncone R, Murray JA, Turner JR, Jabri B. Distinct and synergistic contributions of epithelial stress and adaptive immunity to functions of intraepithelial killer cells and active celiac disease. 2015. Gastroenterology. 149, 681-691 e610. PMC4550536
PDF PUBMED
Powers ME, Becker RE, Sailer A, Turner JR, Bubeck Wardenburg J. Synergistic action of Staphylococcus aureus alpha-toxin on platelets and myeloid lineage cells contributes to lethal sepsis. 2015. Cell Host Microbe. 17, 775-787. PMC4642999
PDF PUBMED
Edelblum KL, Singh G, Lingaraju A, Turner JR. Gammadelta Intraepithelial lymphocyte migration limits transepithelial pathogen invasion and systemic disease in mice. 2015. Gastroenterology. 148, 1417-1426. PMC4685713
PDF PUBMED
Turner JR, Goldenring JR, Wells RG, Brounstein LM, Dubnansky EC. Cellular and Molecular Gastroenterology and Hepatology: The evolution of AGA publishing. 2014. Gastroenterology. 146, 1143-1144
PDF
Konda VJ, Koons A, Siddiqui UD, Xiao SY, Turner JR, Waxman I. Optical biopsy approaches in Barrett’s esophagus with next-generation optical coherence tomography. 2014. Gastrointest Endosc. 80, 516-517
PDF PUBMED
Wu LL, Peng WH, Kuo WT, Huang CY, Ni YH, Lu KS, Turner JR, Yu LC. Commensal bacterial endocytosis in epithelial cells is dependent on myosin light chain kinase-activated brush border fanning by interferon-gamma. 2014. Am J Pathol. 184, 2260-2274. PMC4188866
PDF PUBMED
Barry AK, Tabdili H, Muhamed I, Wu J, Shashikanth N, Gomez GA, Yap AS, Gottardi CJ, de Rooij J, Wang N, Leckband DE. α-catenin cytomechanics–role in cadherin-dependent adhesion and mechanotransduction. 2014. Journal of cell science. 127 (8), 1779-1791. PMC3986676
PUBMED
Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR. Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. 2014. Sci Transl Med. 6, 243ra287. PMC4161673
PDF PUBMED
Illa, X., S. Vila, J. Yeste, C. Peralta, J. Gracia-Sancho, R. Villa. A novel modular bioreactor to in vitro study the hepatic sinusoid. 2014. PLoS ONE. 9, e111864. PMC4222955
PUBMED
Ma K, Malhotra P, Soni V, Hedroug O, Annaba F, Dudeja A, Shen L, Turner JR, Khramtsova EA, Saksena S, Dudeja PK, Gill RK, Alrefai WA. Overactivation of intestinal SREBP2 in mice increases serum cholesterol. 2014. PLoS ONE. 9, e84221. PMC3896331
PDF PUBMED
Chen MM, Zahs A, Brown MM, Ramirez L, Turner JR, Choudhry MA, Kovacs EJ. An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice. 2014. Am J Physiol Gastrointest Liver Physiol. 307, G711-718. PMC4187067
PDF PUBMED
Prathima Nandivada, Deborah Nagle. Surgical therapies for fecal incontinence. 2014. Current opinion in gastroenterology. 30(1), 69-74. 24232369
Turner JR. The gastrointestinal tract. 2014. Robbins and Cotran Pathologic Basis of Disease. 9th Ed, 749-819
PDF
Guozhu Yang, Pingqian Bao, Lie Zhang, Zhaoying Lyu, Bin Zhou, Keling Chen, Su Peng, Yi Wang, Longpei Yao, Yin Zhou, Yuan Li. Critical role of myeloid differentiation factor 88 in necrotizing enterocolitis.. 2014. Pediatric Research. Jun;75(6), 707-715. PMID: 24614801
PUBMED
Odenwald MA, Turner JR. Not ready for prime time: real-time narrow-band imaging for small colorectal polyps. 2014. Practice update, Gastroenterology
PUBMED
Turner JR, Buschmann MM, Romero-Calvo I, Sailer A, Shen L. The role of molecular remodeling in differential regulation of tight junction permeability. 2014. Semin Cell Dev Biol. 36, 204-212. PMC4253049
PDF PUBMED
Yu LC, Shih YA, Wu LL, Lin YD, Kuo WT, Peng WH, Lu KS, Wei SC, Turner JR, Ni YH. Enteric dysbiosis promotes antibiotic-resistant bacterial infection: systemic dissemination of resistant and commensal bacteria through epithelial transcytosis. 2014. Am J Physiol Gastrointest Liver Physiol. 307, G824-835. PMC4214854
PDF PUBMED
Perera J, Liu X, Zhou Y, Joseph NE, Meng L, Turner JR, Huang H. Insufficient autoantigen presentation and failure of tolerance in a mouse model of rheumatoid arthritis. 2013. Arthritis and rheumatism. 65, 2847-2856. PMC3923054
PDF PUBMED
Guimerà A, Illa X, Traver E, Plata-Cordero M, Yeste J, Herrero C, Lagunas C, Maldonado MJ, Villa R. Flexible probe for in vivo quantification of corneal epithelium permeability through non-invasive tetrapolar impedance measurements. 2013. Biomedical Microdevices. 15, 849-858
PUBMED
Rubin DT, Huo D, Kinnucan JA, Sedrak MS, McCullom NE, Bunnag AP, Raun-Royer EP, Cohen RD, Hanauer SB, Hart J, Turner JR. Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study. 2013. Clin Gastroenterol Hepatol. 11, 1601-1608 e1601-1604. PMC3840031
PDF PUBMED
Turner JR. Reply to Skarupski and Keshavarzian. 2013. Gastroenterology. 144, e22-23
PDF PUBMED
Buschmann MM, Shen L, Rajapakse H, Raleigh DR, Wang Y, Wang Y, Lingaraju A, Zha J, Abbott E, McAuley EM, Breskin LA, Wu L, Anderson K, Turner JR, Weber CR. Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. 2013. Mol Biol Cell. 24, 3056-3068. PMC3784380
PDF PUBMED
Turner ES, Turner JR. Expanding the Lauren classification: a new gastric cancer subtype?. 2013. Gastroenterology. 145, 505-508
PDF PUBMED
Eileen Cowan, Prathima Nandivada, Mark Puder. Fish oil-based lipid emulsion in the treatment of parenteral nutrition-associated liver disease. 2013. Current opinion in pediatrics. 25(2), 193-200. 23407182
Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. 2013. Gastroenterology. 145, 407-415. PMC3722284
PDF PUBMED
Odenwald MA, Turner JR. Intestinal permeability defects: is it time to treat?. 2013. Clin Gastroenterol Hepatol. 11, 1075-1083. PMC3758766
PDF PUBMED
P Nandivada 1 , E Cowan, S J Carlson, M Chang, K M Gura, M Puder. Mechanisms for the effects of fish oil lipid emulsions in the management of parenteral nutrition-associated liver disease. 2013. Prostaglandins, leukotrienes, and fatty acids. 89(4), 153-8. 23602846
Prathima Nandivada, Sarah J Carlson, Eileen Cowan, Melissa I Chang, Kathleen M Gura, Mark Puder. Role of parenteral lipid emulsions in the preterm infant. 2013. Early Human Development. 89(2), 45-9. 23998451
Jeffrey J Siracuse, Prathima Nandivada, Kristina A Giles, Allen D Hamdan, Mark C Wyers, Elliot L Chaikof, Frank B Pomposelli, Marc L Schermerhorn. Prosthetic graft infections involving the femoral artery. 2013. Journal of Vascular Surgery. 57(3), 700-5. 23312940
Bergmann KR, Liu SX, Tian R, Kushnir A, Turner JR, Li HL, Chou PM, Weber CR, De Plaen IG. Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis. 2013. Am J Pathol. 182, 1595-1606. PMC3644725
PDF PUBMED
Prathima Nandivada, Sarah J Carlson, Melissa I Chang, Eileen Cowan, Kathleen M Gura, Mark Puder. Treatment of parenteral nutrition-associated liver disease: the role of lipid emulsions. 2013. Advances in nutrition. 4(6), 711-7. 24228202
Bouyer PG, Tang X, Weber CR, Shen L, Turner JR, Matthews JB. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. 2013. Am J Physiol Gastrointest Liver Physiol. 304, G142-156. PMC3543646
PDF PUBMED
Sarah J Carlson, Melissa I Chang, Prathima Nandivada, Eileen Cowan, Mark Puder. Neonatal intestinal physiology and failure. 2013. Seminars in pediatric surgery. 22(4), 190-4. 24331093
Edelblum KL, Shen L, Weber CR, Marchiando AM, Clay BS, Wang Y, Prinz I, Malissen B, Sperling AI, Turner JR. Dynamic migration of gammadelta intraepithelial lymphocytes requires occludin. 2012. Proc Natl Acad Sci U S A. 109, 7097-7102. PMC3345021
PDF PUBMED
Turner JR. Continuing attrition of physician-scientists (CAPS): a preventable syndrome?. 2012. Gastroenterology. 143, 511-515 e511
PDF PUBMED
Langer MD, Guo H, Shashikanth N, Pierce JM, Leckband DE. N-glycosylation alters cadherin-mediated intercellular binding kinetics. 2012. Journal of cell science. 125 (10), 2478-2485
PUBMED
Turner JR, Lingen MW. The oral cavity and gastrointestinal tract. 2012. Basic Pathology. 9th Ed, 551-603
PDF
Bradford EM, Turner ES, Turner JR. Understanding the epithelial barrier in IBD. 2012. Crohn's Disease and Ulcerative Colitis. 75-84
PDF
Nalle SC, Turner JR. Endothelial and epithelial barriers in graft-versus-host disease. 2012. Biology and Regulation of Blood-Tissue Barriers. 105-131
PDF
Zahs A, Bird MD, Ramirez L, Turner JR, Choudhry MA, Kovacs EJ. Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury. 2012. Am J Physiol Gastrointest Liver Physiol. 303, G705-712. PMC3468533
PDF PUBMED
Hwang S, Zimmerman NP, Agle KA, Turner JR, Kumar SN, Dwinell MB. E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 protein during restitution. 2012. J Biol Chem. 287, 22227-22240. PMC3381184
PDF PUBMED
Prathima Nandivada, Vitaly Poylin, Deborah Nagle. Advances in the surgical management of inflammatory bowel disease. 2012. Current opinion in gastroenterology. 28(1), 47-51. 22134218
Zimmerman NP, Kumar SN, Turner JR, Dwinell MB. Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA. 2012. Inflamm Bowel Dis. 18, 1081-1091. PMC3258471
PDF PUBMED
Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, Weber CR, Turner JR, He XC, Katzman RB, Li L, Barrett TA. Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis. 2012. Gastroenterology. 139, 869-881, 881 e861-869. PMC2930080
PDF PUBMED
Ma TY, Anderson JM, Turner JR. Tight junctions and the intestinal barrier. 2012. Physiology of the Gastrointestinal Tract. 1041-1088
PDF
Cunningham KE, Turner JR. Myosin light chain kinase: pulling the strings of epithelial tight junction function. 2012. Ann N Y Acad Sci. 1258, 34-42. PMC3384706
PDF PUBMED
Prathima Nandivada, Kiran H Lagisetty, Kristina Giles, Frank B Pomposelli, Elliot L Chaikof, Marc L Schermerhorn, Mark C Wyers, Allen D Hamdan. The impact of endovascular procedures on fellowship training in lower extremity revascularization. 2012. Journal of Vascular Surgery. 55(6), 1814-20. 22608046
Carey HV, Pike AC, Weber CR, Turner JR, Visser A, Beijer-Liefers SC, Bouma HR, Kroese FG. Impact of hibernation on gut microbiota and intestinal barrier function in ground squirrels. 2012. Living in a seasonal world. 281-291
PUBMED
N Labropoulos, P Nandivada, K Bekelis. Stroke of the posterior cerebral circulation. 2011. International Angiology. 30(2), 105-14. 21427646
Raleigh DR, Boe DM, Yu D, Weber CR, Marchiando AM, Bradford EM, Wang Y, Wu L, Schneeberger EE, Shen L, Turner JR. Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. 2011. J Cell Biol. 193, 565-582. PMC3087007
SUMMARY PDF PUBMED
Fu J, Wei B, Wen T, Johansson ME, Liu X, Bradford E, Thomsson KA, McGee S, Mansour L, Tong M, McDaniel JM, Sferra TJ, Turner JR, Chen H, Hansson GC, Braun J, Xia L. Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. 2011. J Clin Invest. 121, 1657-1666. PMC3069788
PDF PUBMED
Graham WV, Magis AT, Bailey KM, Turner JR, Ostrov DA. Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3. 2011. Acta Crystallogr Sect F Struct Biol Cryst Commun. 67, 221-223. PMC3034612
PDF PUBMED
Zahavi EE, Lieberman JA, Donnenberg MS, Nitzan M, Baruch K, Rosenshine I, Turner JR, Melamed-Book N, Feinstein N, Zlotkin-Rivkin E, Aroeti B. Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity. 2011. Mol Biol Cell. 22, 2436-2447. PMC3135470
PDF PUBMED
Guan Y, Watson AJ, Marchiando AM, Bradford E, Shen L, Turner JR, Montrose MH. Redistribution of the tight junction protein ZO-1 during physiological shedding of mouse intestinal epithelial cells. 2011. Am J Physiol Cell Physiol. 300, C1404-1414. PMC3118625
PDF PUBMED
Zoccali M, Cipriani N, Fichera A, Turner JR, Krane M. Acute appendicitis secondary to a granular cell tumor of the appendix in a 19-year-old male. 2011. J Gastrointest Surg. 15, 1482-1485
PDF PUBMED
Piontek J, Fritzsche S, Cording J, Richter S, Hartwig J, Walter M, Yu D, Turner JR, Gehring C, Rahn HP, Wolburg H, Blasig IE. Elucidating the principles of the molecular organization of heteropolymeric tight junction strands. 2011. Cellular and molecular life sciences : CMLS. 68, 3903-3918. PMC4336547
PDF PUBMED
Kolodziej LE, Lodolce JP, Chang JE, Schneider JR, Grimm WA, Bartulis SJ, Zhu X, Messer JS, Murphy SF, Reddy N, Turner JR, Boone DL. TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. 2011. PloS one. 6, e26352. PMC3198775
PDF PUBMED
Temkin SM, Turner JR, Lengyel ER. Acute inflammatory reaction following placement of sodium hyaluronate-carboxymethylcellulose barrier in a young woman undergoing gynecologic surgery: a case report. 2011. J Reprod Med. 56, 71-74
PDF PUBMED
Mirzapoiazova T, Moitra J, Moreno-Vinasco L, Sammani S, Turner JR, Chiang ET, Evenoski C, Wang T, Singleton PA, Huang Y, Lussier YA, Watterson DM, Dudek SM, Garcia JG. Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury. 2011. American Journal of Respiratory Cell and Molecular Biology. 44, 40-52. PMC3028257
PDF PUBMED
Lin R, Murtazina R, Cha B, Chakraborty M, Sarker R, Chen TE, Lin Z, Hogema BM, de Jonge HR, Seidler U, Turner JR, Li X, Kovbasnjuk O, Donowitz M. D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. 2011. Gastroenterology. 140, 560-571. PMC3031713
PDF PUBMED
Paschoud S, Yu D, Pulimeno P, Jond L, Turner JR, Citi S. Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions. 2011. Molecular membrane biology. 28, 123-135. PMC4336546
PDF PUBMED
Shen L, Weber CR, Raleigh DR, Yu D, Turner JR. Tight junction pore and leak pathways: a dynamic duo. 2011. Annual review of physiology. 73, 283-309. PMC4655434
PDF PUBMED
Marchiando AM, Shen L, Graham WV, Edelblum KL, Duckworth CA, Guan Y, Montrose MH, Turner JR, Watson AJ. The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. 2011. Gastroenterology. 140, 1208-1218 e1201-1202. PMC3066304
PDF PUBMED
Yu D, Marchiando AM, Weber CR, Raleigh DR, Shen L, Turner JR, Wang Y. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. 2010. Proc Natl Acad Sci U S A. 107, 8237-8241. PMC2889526
PDF PUBMED
Weber CR, Raleigh DR, Su L, Shen L, Sullivan EA, Wang Y, Turner JR. Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. 2010. J Biol Chem. 285, 12037-12046. PMC2852941
PDF PUBMED
Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR. Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. 2010. Mol Biol Cell. 21, 1200-1213. PMC2847524
PDF PUBMED
Li H, Liu XS, Yang X, Wang Y, Wang Y, Turner JR, Liu X. Phosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore-microtubule attachments. 2010. EMBO J. 29, 2953-2965. PMC2944045
PDF PUBMED
Turner JR. CD95 promotes tumour growth. 2010. Nature. 465, 492-496. PMC2879093
PDF PUBMED
Lopez JP, Turner JR, Philipson LH. Glucose-induced ERM protein activation and translocation regulates insulin secretion. 2010. Am J Physiol Endocrinol Metab. 299, E772-785. PMC2980361
PDF PUBMED
Lissner S, Nold L, Hsieh CJ, Turner JR, Gregor M, Graeve L, Lamprecht G. Activity and PI3-kinase dependent trafficking of the intestinal anion exchanger downregulated in adenoma depend on its PDZ interaction and on lipid rafts. 2010. Am J Physiol Gastrointest Liver Physiol. 299, G907-920. PMC5142450
PDF PUBMED
Marchiando AM, Shen L, Graham WV, Weber CR, Schwarz BT, Austin JR, 2nd, Raleigh DR, Guan Y, Watson AJ, Montrose MH, Turner JR. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. 2010. J Cell Biol. 189, 111-126. PMC2854371
PDF PUBMED
Tang Y, Clayburgh DR, Mittal N, Goretsky T, Dirisina R, Zhang Z, Kron M, Ivancic D, Katzman RB, Grimm G, Lee G, Fryer J, Nusrat A, Turner JR, Barrett TA. Epithelial NF-kappaB enhances transmucosal fluid movement by altering tight junction protein composition after T cell activation. 2010. Am J Pathol. 176, 158-167. PMC2797878
PDF PUBMED
Park SM, Chen L, Zhang M, Ashton-Rickardt P, Turner JR, Peter ME. CD95 is cytoprotective for intestinal epithelial cells in colitis. 2010. Inflamm Bowel Dis. 16, 1063-1070
PDF PUBMED
Pekow JR, Hetzel JT, Rothe JA, Hanauer SB, Turner JR, Hart J, Noffsinger A, Huo D, Rubin DT. Outcome after surveillance of low-grade and indefinite dysplasia in patients with ulcerative colitis. 2010. Inflamm Bowel Dis. 16, 1352-1356. PMC3046461
PDF PUBMED
Ben T Atkinson, Reema Jasuja, Vivien M Chen, Prathima Nandivada, Bruce Furie, Barbara C Furie. Laser-induced endothelial cell activation supports fibrin formation. 2010. Blood. 116(22), 4675-83. 20675401
Nicos Labropoulos 1 , Prathima Nandivada, Kimon Bekelis. Prevalence and impact of the subclavian steal syndrome. 2010. Annals of Surgery. 252(1), 166-70. 20531004
Chen L, Park SM, Turner JR, Peter ME. Cell death in the colonic epithelium during inflammatory bowel diseases: CD95/Fas and beyond. 2010. Inflamm Bowel Dis. 16, 1071-1076
PDF PUBMED
Mykoniatis A, Shen L, Fedor-Chaiken M, Tang J, Tang X, Worrell RT, Delpire E, Turner JR, Matlin KS, Bouyer P, Matthews JB. Phorbol 12-myristate 13-acetate-induced endocytosis of the Na-K-2Cl cotransporter in MDCK cells is associated with a clathrin-dependent pathway. 2010. Am J Physiol Cell Physiol. 298, C85-97. PMC2806153
PDF PUBMED
Royan SV, Jones RM, Koutsouris A, Roxas JL, Falzari K, Weflen AW, Kim A, Bellmeyer A, Turner JR, Neish AS, Rhee KJ, Viswanathan VK, Hecht GA. Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-kappaB activation. 2010. Mol Microbiol. 78, 1232-1245. PMC3325542
PDF PUBMED
Rajapakse HE, Gahlaut N, Mohandessi S, Yu D, Turner JR, Miller LW. Time-resolved luminescence resonance energy transfer imaging of protein-protein interactions in living cells. 2010. Proc Natl Acad Sci U S A. 107, 13582-13587. PMC2922258
PDF PUBMED
Marchiando AM, Graham WV, Turner JR. Epithelial barriers in homeostasis and disease. 2010. Annu Rev Pathol. 5, 119-144
PDF PUBMED
Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. 2009. Gastroenterology. 136, 551-563. PMC2712351
PDF PUBMED
Nalle SC, Turner JR. Menetrier’s disease therapy: rebooting mucosal signaling. 2009. Sci Transl Med. 1, 8ps10
PDF PUBMED
Nalle SC, Turner JR. Epithelium, tear down this wall!. 2009. Cell Host Microbe. 5, 1-2
PDF PUBMED
Wroblewski LE, Shen L, Ogden S, Romero-Gallo J, Lapierre LA, Israel DA, Turner JR, Peek RM, Jr. Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation. 2009. Gastroenterology. 136, 236-246. PMC2678540
PDF PUBMED
Suzuki T, Elias BC, Seth A, Shen L, Turner JR, Giorgianni F, Desiderio D, Guntaka R, Rao R. PKC eta regulates occludin phosphorylation and epithelial tight junction integrity. 2009. Proc Natl Acad Sci U S A. 106, 61-66. PMC2629239
PDF PUBMED
Turner JR. Intestinal mucosal barrier function in health and disease. 2009. Nat Rev Immunol. 9, 799-809
PDF PUBMED
Snoeks L, Weber CR, Wasland K, Turner JR, Vainder C, Qi W, Savkovic SD. Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation. 2009. Lab Invest. 89, 1053-1062. PMC3048782
PDF PUBMED
Edelblum KL, Turner JR. The tight junction in inflammatory disease: communication breakdown. 2009. Curr Opin Pharmacol. 9, 715-720. PMC2788114
PDF PUBMED
Lamprecht G, Hsieh CJ, Lissner S, Nold L, Heil A, Gaco V, Schafer J, Turner JR, Gregor M. Intestinal anion exchanger down-regulated in adenoma (DRA) is inhibited by intracellular calcium. 2009. J Biol Chem. 284, 19744-19753. PMC2740598
PDF PUBMED
Lamprecht G, Gaco V, Turner JR, Natour D, Gregor M. Regulation of the intestinal anion exchanger DRA (downregulated in adenoma). 2009. Ann N Y Acad Sci. 1165, 261-266
PDF PUBMED
Shen L, Su L, Turner JR. Mechanisms and functional implications of intestinal barrier defects. 2009. Dig Dis. 27, 443-449. PMC2814011
PDF PUBMED
Elias BC, Suzuki T, Seth A, Giorgianni F, Kale G, Shen L, Turner JR, Naren A, Desiderio DM, Rao R. Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions. 2009. J Biol Chem. 284, 1559-1569. PMC2615497
PDF PUBMED
Graham WV, Marchiando AM, Shen L, Turner JR. No static at all. 2009. Ann N Y Acad Sci. 1165, 314-322. PMC2768559
PDF PUBMED
Esmaili A, Nazir SF, Borthakur A, Yu D, Turner JR, Saksena S, Singla A, Hecht GA, Alrefai WA, Gill RK. Enteropathogenic Escherichia coli infection inhibits intestinal serotonin transporter function and expression. 2009. Gastroenterology. 137, 2074-2083. PMC3727418
PDF PUBMED
Mukherjee A, Morosky SA, Shen L, Weber CR, Turner JR, Kim KS, Wang T, Coyne CB. Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. 2009. J Biol Chem. 284, 6486-6494. PMC5405323
PDF PUBMED
Oto A, Zhu F, Kulkarni K, Karczmar GS, Turner JR, Rubin D. Evaluation of diffusion-weighted MR imaging for detection of bowel inflammation in patients with Crohn’s disease. 2009. Acad Radiol. 16, 597-603. PMC2721917
PDF PUBMED
Liu S, Yang W, Shen L, Turner JR, Coyne CB, Wang T. Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection. 2009. J Virol. 83, 2011-2014. PMC2643775
PDF PUBMED
Turner JR, Odze RD. Polyps of the stomach. 2009. Surgical Pathology of the Gastrointestinal Tract, Liver, Biliary Tract and Pancreas. 2nd Ed, 415-445
PDF
Turner JR. The gastrointestinal tract. 2009. Robbins and Cotran Pathologic Basis of Disease. 8th Ed, 763-831
PDF
Chen B, Yates E, Huang Y, Kogut P, Ma L, Turner JR, Tao Y, Camoretti-Mercado B, Lang D, Svensson EC, Garcia JG, Gruber PJ, Morrisey EE, Solway J. Alternative promoter and GATA5 transcripts in mouse. 2009. Am J Physiol Gastrointest Liver Physiol. 297, G1214-1222. PMC2850090
PDF PUBMED
Turner JR, Madara JL. Epithelia: biological principles of organization. 2009. Textbook of Gastroenterology, 5th edition. 169-186
PDF
Yu LC, Huang CY, Kuo WT, Sayer H, Turner JR, Buret AG.. SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis. 2008. Int J Parasitol. 38, 923-934. PMC2693066
PDF PUBMED
Shen L, Weber CR, Turner JR. The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. 2008. J Cell Biol. 181, 683-695. PMC2386107
PDF PUBMED
Yu D, Turner JR. Stimulus-induced reorganization of tight junction structure: the role of membrane traffic. 2008. Biochim Biophys Acta. 1778, 709-716. PMC2374757
PDF PUBMED
Snoeks L, Weber CR, Turner JR, Bhattacharyya M, Wasland K, Savkovic SD. Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells. 2008. Infect Immun. 76, 4677-4685. PMC2546851
PDF PUBMED
Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. 2008. Alcohol. 42, 349-361. PMC2614138
PDF PUBMED
Weber CR, Nalle SC, Tretiakova M, Rubin DT, Turner JR. Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. 2008. Lab Invest. 88, 1110-1120. PMC2586671
PDF PUBMED
Crawford JM, Ketcham CM, Braylan R, Morel L, Terada N, Turner JR, Yachnis AT. The publishing game: reflections of an editorial team. 2008. Lab Invest. 88, 1258-1263
PDF PUBMED
Shen L, Turner JR. Intercellular junctions: actin the PARt. 2008. Curr Biol. 18, R1014-1017
PDF PUBMED
Moitra J, Evenoski C, Sammani S, Wadgaonkar R, Turner JR, Ma SF, Garcia JG. A transgenic mouse with vascular endothelial over-expression of the non-muscle myosin light chain kinase-2 isoform is susceptible to inflammatory lung injury: role of sexual dimorphism and age. 2008. Transl Res. 151, 141-153. PMC2693047
PDF PUBMED
Zaborina O, Holbrook C, Chen Y, Long J, Zaborin A, Morozova I, Fernandez H, Wang Y, Turner JR, Alverdy JC. Structure-function aspects of PstS in multi-drug-resistant Pseudomonas aeruginosa. 2008. PLoS Pathog. 4, e43. PMC2242829
PDF PUBMED
Gill RK, Shen L, Turner JR, Saksena S, Alrefai WA, Pant N, Esmaili A, Dwivedi A, Ramaswamy K, Dudeja PK. Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cellsg. 2008. Am J Physiol Gastrointest Liver Physiol. 295, G700-708. PMC2575920
PDF PUBMED
Gill RK, Pant N, Saksena S, Singla A, Nazir TM, Vohwinkel L, Turner JR, Goldstein J, Alrefai WA, Dudeja PK. Function, expression, and characterization of the serotonin transporter in the native human intestine. 2008. Am J Physiol Gastrointest Liver Physiol. 294, G254-262. PMC4880408
PDF PUBMED
Annaba F, Sarwar Z, Kumar P, Saksena S, Turner JR, Dudeja PK, Gill RK, Alrefai WA. Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. 2008. Am J Physiol Gastrointest Liver Physiol. 294, G489-497. PMC4880014
PDF PUBMED
Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells. 2007. Inflamm Bowel Dis. 13, 1202-1211
PDF PUBMED
Zaborina O, Lepine F, Xiao G, Valuckaite V, Chen Y, Li T, Ciancio M, Zaborin A, Petrof EO, Turner JR, Rahme LG, Chang E, Alverdy JC. Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa. 2007. PLoS Pathog. 3, e35. PMC1828698
PDF PUBMED
Su L, Turner JR. Got guts? Need nerve!. 2007. Gastroenterology. 132, 1615-1618
PDF PUBMED
Patel NJ, Zaborina O, Wu L, Wang Y, Wolfgeher DJ, Valuckaite V, Ciancio MJ, Kohler JE, Shevchenko O, Colgan SP, Chang EB, Turner JR, Alverdy JC. Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa. 2007. Am J Physiol Gastrointest Liver Physiol. 292, G134-142. PMC2694754
PDF PUBMED
Treede I, Braun A, Sparla R, Kuhnel M, Giese T, Turner JR, Anes E, Kulaksiz H, Fullekrug J, Stremmel W, Griffiths G, Ehehalt R. Anti-inflammatory effects of phosphatidylcholine. 2007. J Biol Chem. 282, 27155-27164. PMC2693065
PDF PUBMED
Schwarz BT, Wang F, Shen L, Clayburgh DR, Su L, Wang Y, Fu YX, Turner JR. LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. 2007. Gastroenterology. 132, 2383-2394. PMC2709832
PDF PUBMED
Kulke MH, Turner JR, Meyerhardt J. Colorectal cancer: epidemiology, histology, diagnosis, and staging. 2007. Colorectal Cancer from the Dana-Farber Cancer Institute Handbook Series. 23-56
Fichera A, Little N, Jagadeeswaran S, Dougherty U, Sehdev A, Mustafi R, Cerda S, Yuan W, Khare S, Tretiakova M, Gong C, Tallerico M, Cohen G, Joseph L, Hart J, Turner JR, Bissonnette M. Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis. 2007. Cancer Res. 67, 827-835. PMC2705749
PDF PUBMED
Coyne CB, Shen L, Turner JR, Bergelson JM. Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. 2007. Cell Host Microbe. 2, 181-192. PMC2719558
PDF PUBMED
Sun Q, Weber CR, Sohail A, Bernardo MM, Toth M, Zhao H, Turner JR, Fridman R. MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties. 2007. J Biol Chem. 282, 21998-22010. PMC1978545
PDF PUBMED
Gill RK, Borthakur A, Hodges K, Turner JR, Clayburgh DR, Saksena S, Zaheer A, Ramaswamy K, Hecht G, Dudeja PK. Mechanism underlying inhibition of intestinal apical Cl/OH exchange following infection with enteropathogenic E. coli. 2007. J Clin Invest. 117, 428-437. PMC1770946
PDF PUBMED
Weber CR, Turner JR. Inflammatory bowel disease: is it really just another break in the wall?. 2007. Gut. 56, 6-8. PMC1856658
PDF PUBMED
Moyer RA, Wendt MK, Johanesen PA, Turner JR, Dwinell MB. Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia. 2007. Lab Invest. 87, 807-817. PMC2693067
PDF PUBMED
Turner JR, Clayburgh DR, Musch MW, Leitges M, Fu YX. Response to field. 2006. J Clin Invest. 116, 3088-3089
PDF PUBMED
Shen L, Black ED, Witkowski ED, Lencer WI, Guerriero V, Schneeberger EE, Turner JR. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. 2006. J Cell Sci. 119, 2095-2106
PDF PUBMED
Shen L, Turner JR. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. 2006. Am J Physiol Gastrointest Liver Physiol. 290, G577-582
PDF PUBMED
Clayburgh DR, Turner JR. Mechanisms of ion transport regulation by microfilaments. 2006. Advances in Molecular and Cell Biology: Aspects of the Cytoskeleton. 285-305
Hu Z, Wang Y, Graham WV, Su L, Musch MW, Turner JR. MAPKAPK-2 is a critical signaling intermediate in NHE3 activation following Na+-glucose cotransporthu. 2006. J Biol Chem. 281, 24247-24253
PDF PUBMED
Turner JR. Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application. 2006. Am J Pathol. 169, 1901-1909. PMC1762492
PDF PUBMED
Graham WV, Turner JR. Introduction to the host and bacterial pathogens. Overview of the epithelial cell. 2006. Bacterial-Epithelial Cell Cross-Talk: Molecular Mechanisms in Pathogenesis. 3-29
PDF
Rubin DT, Turner JR. Surveillance of dysplasia in inflammatory bowel disease: The gastroenterologist-pathologist partnership. 2006. Clin Gastroenterol Hepatol. 4, 1309-1313. PMC1829445
PDF PUBMED
Graham WV, Wang F, Clayburgh DR, Cheng JX, Yoon B, Wang Y, Lin A, Turner JR. Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. 2006. J Biol Chem. 281, 26205-26215
PDF PUBMED
Gu LZ, Hu WY, Antic N, Mehta R, Turner JR, de Lanerolle P. Inhibiting myosin light chain kinase retards the growth of mammary and prostate cancer cells. 2006. Eur J Cancer. 42, 948-957
PDF PUBMED
Clayburgh DR, Turner JR. Transfection of Caco-2 Cells with siRNA using the siLentFect™ lipid reagent. 2006. Bioradiations. 118, 22-23
PDF
Clayburgh DR, Turner JR. Use of the Bio-plex™ cytokine immunoassay to determine cytokine expression levels in the intestinal mucosa. 2006. Bioradiations. 118, 14-15
PDF
Bullen TF, Forrest S, Campbell F, Dodson AR, Hershman MJ, Pritchard DM, Turner JR, Montrose MH, Watson AJ. Characterization of epithelial cell shedding from human small intestine. 2006. Lab Invest. 86, 1052-1063
PDF PUBMED
Clayburgh DR, Musch MW, Leitges M, Fu YX, Turner JR. Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. 2006. J Clin Invest. 116, 2682-2694. PMC1578628
PDF PUBMED
Blair SA, Kane SV, Clayburgh DR, Turner JR. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. 2006. Lab Invest. 86, 191-201
PDF PUBMED
Wang F, Schwarz BT, Graham WV, Wang Y, Su L, Clayburgh DR, Abraham C, Turner JR. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. 2006. Gastroenterology. 131, 1153-1163. PMC1693969
PDF PUBMED
Zaborina O, Kohler JE, Wang Y, Bethel C, Shevchenko O, Wu L, Turner JR, Alverdy JC. Identification of multi-drug resistant Pseudomonas aeruginosa clinical isolates that are highly disruptive to the intestinal epithelial barrier. 2006. Annals of Clinical Microbiology and Antimicrobials. 5, 14. PMC1513249
PDF PUBMED
Zhang J, Owen CR, Sanders MA, Turner JR, Basson MD. The motogenic effects of cyclic mechanical strain on intestinal epithelial monolayer wound closure are matrix dependent. 2006. Gastroenterology. 131, 1179-1189
PDF PUBMED
Turner JR, Maitra A, Natkunam Y, Rubin BP, Rubin MA, Teitell MA. Bringing pathobiology into focus. 2006. Lab Invest. 86, 632
PDF PUBMED
Yu LC, Turner JR, Buret AG. LPS/CD14 activation triggers SGLT-1-mediated glucose uptake and cell rescue in intestinal epithelial cells via early apoptotic signals upstream of caspase-3. 2006. Exp Cell Res. 312, 3276-3286
PDF PUBMED
Wang F, Graham WV, Witkowski ED, Schwarz BT, Turner JR, Wang Y. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. 2005v. Am J Pathol. 166, 409-419. PMC1237049
PDF PUBMED
Russo JM, Florian P, Shen L, Graham WV, Tretiakova MS, Gitter AH, Mrsny RJ, Turner JR. Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure. 2005. Gastroenterology. 128, 987-1001. PMC1237051
PDF PUBMED
Utech M, Ivanov AI, Samarin SN, Bruewer M, Turner JR, Mrsny RJ, Parkos CA, Nusrat A. Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. 2005. Mol Biol Cell. 16, 5040-5052. PMC1237102
PDF PUBMED
Clayburgh DR, Barrett TA, Tang Y, Meddings JB, Van Eldik LJ, Watterson DM, Clarke LL, Mrsny RJ, Turner JR. Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. 2005. J Clin Invest. 115, 2702-2715. PMC1224297
PDF PUBMED
Wu LR, Zaborina O, Zaborin A, Chang EB, Musch M, Holbrook C, Turner JR, Alverdy JC. Surgical injury and metabolic stress enhance the virulence of the human opportunistic pathogen Pseudomonas aeruginosa. 2005. Surgical infections. 6, 185-195
PDF PUBMED
Wu L, Estrada O, Zaborina O, Bains M, Shen L, Kohler JE, Patel N, Musch MW, Chang EB, Fu YX, Jacobs MA, Nishimura MI, Hancock RE, Turner JR, Alverdy JC. Recognition of host immune activation by Pseudomonas aeruginosa. 2005. Science. 309, 774-777
PDF PUBMED
Marski M, Kandula S, Turner JR, Abraham C. CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. 2005. J Immunol. 175, 7889-7897
PDF PUBMED
Gill RK, Saksena S, Tyagi S, Alrefai WA, Malakooti J, Sarwar Z, Turner JR, Ramaswamy K, Dudeja PK. Serotonin inhibits Na+/H+ exchange activity via 5-HT4 receptors and activation of PKC alpha in human intestinal epithelial cells. 2005. Gastroenterology. 128, 962-974
PDF PUBMED
Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX. The critical role of LIGHT in promoting intestinal inflammation and Crohn’s disease. 2005. J Immunol. 174, 8173-8182
PDF PUBMED
Arvans DL, Vavricka SR, Ren H, Musch MW, Kang L, Rocha FG, Lucioni A, Turner JR, Alverdy J, Chang EB. Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. 2005. Am J Physiol Gastrointest Liver Physiol. 288, G696-704
PDF PUBMED
Yu LC, Flynn AN, Turner JR, Buret AG. SGLT-1-mediated glucose uptake protects intestinal epithelial cells against LPS-induced apoptosis and barrier defects: a novel cellular rescue mechanism?. 2005. FASEB J. 19, 1822-1835
PDF PUBMED
Savkovic SD, Villanueva J, Turner JR, Matkowskyj KA, Hecht G. Mouse model of enteropathogenic Escherichia coli infection. 2005. Infect Immun. 73, 1161-1170. PMC546940
PDF PUBMED
Kimura Y, Turner JR, Braasch DA, Buddington RK. Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine. 2005. Am J Physiol Gastrointest Liver Physiol. 289, G1007-1014
PDF PUBMED
Shiue H, Musch MW, Wang Y, Chang EB, Turner JR. Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation. 2005. J Biol Chem. 280, 1688-1695. PMC1237052
PDF PUBMED
Kohler JE, Zaborina O, Wu L, Wang Y, Bethel C, Chen Y, Shapiro J, Turner JR, Alverdy JC. Components of intestinal epithelial hypoxia activate the virulence circuitry of Pseudomonas. 2005. Am J Physiol Gastrointest Liver Physiol. 288, G1048-1054
PDF PUBMED
Kles KA, Vavricka SR, Turner JR, Musch MW, Hanauer SB, Chang EB. Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum. 2005. Inflamm Bowel Dis. 11, 253-257
PDF PUBMED
Siccardi D, Turner JR, Mrsny RJ. Regulation of intestinal epithelial function: a link between opportunities for macromolecular drug delivery and inflammatory bowel disease. 2005. Adv Drug Deliv Rev. 57, 219-235
PDF PUBMED
Shen L, Turner JR. Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis. 2005. Mol Biol Cell. 16, 3919-3936. PMC1196308
PDF PUBMED
Owens SE, Graham WV, Siccardi D, Turner JR, Mrsny RJ. A strategy to identify stable membrane-permeant peptide inhibitors of myosin light chain kinase. 2005. Pharm Res. 22, 703-709
PDF PUBMED
Shifflett DE, Clayburgh DR, Koutsouris A, Turner JR, Hecht GA. Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo. 2005. Lab Invest. 85, 1308-1324
PDF PUBMED
Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, Turner JR, Nakajima A, Borkan SC, Saubermann LJ. Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells. 2005. Cancer Res. 65, 2251-2259
PDF PUBMED
Zhao H, Shiue H, Palkon S, Wang Y, Cullinan P, Burkhardt JK, Musch MW, Chang EB, Turner JR. Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport. 2004. Proc Natl Acad Sci U S A. 101, 9485-9490. PMC439003
PDF PUBMED
Russo JM, Turner JR. Gastrointestinal tract anatomy, overview. 2004. Encyclopedia of Gastroenterology. 223-227
PDF
Wang J, Anders RA, Wu Q, Peng D, Cho JH, Sun Y, Karaliukas R, Kang HS, Turner JR, Fu YX. Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy. 2004. J Clin Invest. 113, 826-835. PMC362120
PDF PUBMED
Tomson FL, Koutsouris A, Viswanathan VK, Turner JR, Savkovic SD, Hecht G. Differing roles of protein kinase C-zeta in disruption of tight junction barrier by enteropathogenic and enterohemorrhagic Escherichia coli. 2004. Gastroenterology. 127, 859-869
PDF PUBMED
Clayburgh DR, Rosen S, Witkowski ED, Wang F, Blair S, Dudek S, Garcia JG, Alverdy JC, Turner JR. A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability. 2004 . J Biol Chem. 279, 55506-55513. PMC1237105
PDF PUBMED
Clayburgh DR, Shen L, Turner JR. A porous defense: the leaky epithelial barrier in intestinal disease. 2004. Lab Invest. 84, 282-291
PDF PUBMED
Wu L, Zaborina O, Zaborin A, Chang EB, Musch M, Holbrook C, Shapiro J, Turner JR, Wu G, Lee KY, Alverdy JC. High-molecular-weight polyethylene glycol prevents lethal sepsis due to intestinal Pseudomonas aeruginosa. 2004. Gastroenterology. 126, 488-498
PDF PUBMED
Clayburgh DR, Turner JR. Stomach, anatomy. 2004. Encyclopedia of Gastroenterology. 458-462
PDF
Turner JR, Odze RD. Gastric polyps. 2004. Surgical Pathology of the Gastrointestinal Tract, Liver, Biliary Tract and Pancreas. 1st Ed, 267-294
Turner JR. Functional morphology of the intestinal mucosae: From crypts to tips. 2003. Microbial Pathogenesis and the Intestinal Epithelial Cell. 1-22
Hecht G, Turner JR. Bacterial infections of the colon. 2003. Atlas of Gastroenterology. 3rd Ed, 371-376
Kulke MH, Turner JR, Skarin AT. Cancer of the gastrointestinal tract. 2003. Atlas of Diagnostic Oncology. 3rd Ed, 113-162
Edens HA, Levi BP, Jaye DL, Walsh S, Reaves TA, Turner JR, Nusrat A, Parkos CA. Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional. 2002. J Immunol. 169, 476-486
PDF PUBMED
Abner SR, Hill DE, Turner JR, Black ED, Bartlett P, Urban JF, Mansfield LS. Response of intestinal epithelial cells to Trichuris suis excretory-secretory products and the influence on Campylobacter jejuni invasion under in vitro conditions. 2002. J Parasitol. 88, 738-745
PDF PUBMED
Kles KA, Turner JR, Tappenden KA. Enteral nutrients alter enterocyte function within an in vitro model similar to an acute in vivo rat model during hypoxia. 2002. JPEN J Parenter Enteral Nutr. 26, 71-76
PDF PUBMED
Zolotarevsky Y, Hecht G, Koutsouris A, Gonzalez DE, Quan C, Tom J, Mrsny RJ, Turner JR. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. 2002. Gastroenterology. 123, 163-172
PDF PUBMED
Turner JR, Basson MD. Roles of the extracellular matrix and cytoskeleton in intestinal epithelial restitution. 2002. Gastrointestinal Mucosal Repair and Experimental Therapeutics. 1-13
PDF
Hendrickson BA, Turner JR. MMR vaccination, ileal lymphoid nodular hyperplasia, and pervasive develop-mental disorder. 2002. Lancet. 359, 2051-2052
PDF PUBMED
Turner JR, Black ED. NHE3-dependent cytoplasmic alkalinization is triggered by Na(+)-glucose cotransport in intestinal epithelia. 2001. Am J Physiol Cell Physiol. 281, C1533-1541
PDF PUBMED
Yu Y, Rishi AK, Turner JR, Liu D, Black ED, Moshier JA, Majumdar AP. Cloning of a novel EGFR-related peptide: a putative negative regulator of EGFR. 2001. Am J Physiol Cell Physiol. 280, C1083-1089
PDF PUBMED
Furuta GT, Turner JR, Taylor CT, Hershberg RM, Comerford K, Narravula S, Podolsky DK, Colgan SP. Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. 2001. J Exp Med. 193, 1027-1034. PMC2193432
PDF PUBMED
Kinzie JL, Naylor PH, Nathani MG, Peleman RR, Ehrinpreis MN, Lybik M, Turner JR, Janisse JJ, Massanari M, Mutchnick MG. African Americans with genotype 1 treated with interferon for chronic hepatitis C have a lower end of treatment response than Caucasians. 2001. J Viral Hepat. 8, 264-269
PDF PUBMED
Turner JR, Madara JL. Physiological regulation of tight junction permeability by Na+-nutrient cotransport.. 2001. Tight Junctions. 333-347
Nusrat A, von Eichel-Streiber C, Turner JR, Verkade P, Madara JL, Parkos CA. Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins. 2001. Infect Immun. 69, 1329-1336. PMC98024
PDF PUBMED
Guzman CB, Walsh M, Reddy V, Donthireddy V, Mahmood F, Bode A, Turner JR, Jacober SJ, Sowers JR. Altered myosin light-chain phosphorylation in resting platelets from premenopausal women with diabetes. 2001. Metabolism. 50, 151-156
PDF PUBMED
Berglund JJ, Riegler M, Zolotarevsky Y, Wenzl E, Turner JR. Regulation of human jejunal transmucosal resistance and MLC phosphorylation by Na(+)-glucose cotransport. 2001. Am J Physiol Gastrointest Liver Physiol. 281, G1487-1493
PDF PUBMED
Turner JR, Liu L, Fligiel SE, Jaszewski R, Majumdar AP. Aging alters gastric mucosal responses to epidermal growth factor and transforming growth factor-alpha. 2000. Am J Physiol Gastrointest Liver Physiol. 278, G805-810. G805-810
PDF PUBMED
Turner JR. Show me the pathway! Regulation of paracellular permeability by Na(+)-glucose cotransport. 2000. Adv Drug Deliv Rev. 41, 265-281
PDF PUBMED
Turner JR. ‘Putting the squeeze’ on the tight junction: understanding cytoskeletal regulation. 2000. Semin Cell Dev Biol. 11, 301-308
PDF PUBMED
Turner JR, Black ED, Ward J, Tse CM, Uchwat FA, Alli HA, Donowitz M, Madara JL, Angle JM. Transepithelial resistance can be regulated by the intestinal brush border Na+-H+ exchanger NHE3. 2000. Am J Physiol Cell Physiol. 279, C1918-1924. C1918-1924
PDF PUBMED
Turner JR, Cohen DE, Mrsny RJ, Madara JL. Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport. 2000. Digestive diseases and sciences. 45, 2122-2126
PDF PUBMED
Nusrat A, Turner JR, Madara JL. Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells. 2000. Am J Physiol Gastrointest Liver Physiol. 279, G851-857
PDF PUBMED
Goldstein NS, Turner JR. Pericolonic tumor deposits in patients with T3N+MO colon adenocarcinomas: Markers of reduced disease free survival and intra-abdominal metastases and their implications for TNM classification. 2000. Cancer. 88, 2228-2238
PDF PUBMED
Turner JR, Torres CM, Wang HH, Shahsafaei A, Richards WG, Sugarbaker D, Odze RD. Preoperative chemoradiotherapy alters the expression and prognostic significance of adhesion molecules in Barrett’s-associated adenocarcinoma. 2000. Hum Pathol. 31, 347-353
PDF PUBMED
Yoshimura FK, Wang T, Yu F, Kim HR, Turner JR.. Mink cell focus-forming murine leukemia virus infection induces apoptosis of thymic lymphocytes. 2000. J Virol. 74, 8119-8126. PMC112345
PDF PUBMED
Kaur J, Turner JR, Singh P, Al-Katib A. Multiple myeloma in the liver. 2000. Am J Hematol. 65, 290
PDF PUBMED
Turner JR, Angle JM, Black ED, Joyal JL, Sacks DB, Madara JL. Protein kinase C-dependent regulation of transepithelial resistance: the roles of myosin light chain and myosin light chain kinase. 1999. Am J Physiol. 277, C554-562
PDF PUBMED
Turner JR, Tartakoff AM. On the relation between distinct components of the cytoskeleton: an epitope shared by intermediate filaments, microfilaments and cytoplasmic foci. 1999. Eur J Cell Biol. 51, 259-264
PDF PUBMED
Saubermann LJ, Probert CS, Christ AD, Chott A, Turner JR, Stevens AC, Balk SP, Blumberg RS. Evidence of T cell receptor beta-chain patterns in inflammatory and noninflammatory bowel disease states. 1999. Am J Physiol. 276, G613-621
PDF PUBMED
Glickman JN, Torres C, Wang HH, Turner JR, Shahsafaei A, Richards WG, Sugarbaker DJ, Odze RD. The prognostic significance of lymph node micrometastasis in patients with esophageal carcinoma. 1999. Cancer. 85, 769-778
PDF PUBMED
Turner JR, Jimenez RE. Reply to Mogyorosi and Schubert. 1999. Gastroenterology. 116, 219-220
PDF PUBMED
Torres C, Turner JR, Wang HH, Richards W, Sugarbaker D, Shahsafaei A, Odze RD. Pathologic prognostic factors in Barrett’s associated adenocarcinoma: a follow-up study of 96 patients. 1999. Cancer. 85, 520-528
PDF PUBMED
Jimenez RE, Price DA, Pinkus GS, Owen WF, Jr., Lazarus JM, Kay J, Turner JR. Development of gastrointestinal beta2-microglobulin amyloidosis correlates with time on dialysis. 1998. Am J Surg Pathol. 22, 729-735
PDF PUBMED
Liu L, Turner JR, Yu Y, Khan AJ, Jaszewski R, Fligiel SE, Majumdar AP. Differential expression of EGFR during early reparative phase of the gastric mucosa between young and aged rats. 1998. Am J Physiol. 275, G943-950
PDF PUBMED
Probert CS, Christ AD, Saubermann LJ, Turner JR, Chott A, Carr-Locke D, Balk SP, Blumberg RS. Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition. 1997. J Immunol. 158, 1941-1948
PDF PUBMED
Aster JC, Robertson ES, Hasserjian RP, Turner JR, Kieff E, Sklar J. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and. 1997. J Biol Chem. 272, 11336-11343
PDF PUBMED
Turner JR, Odze RD, Crum CP, Resnick MB. MN antigen expression in normal, preneoplastic, and neoplastic esophagus: a clinicopathological study of a new cancer-associated biomarker. 1997. Hum Pathol. 28, 740-744
PDF PUBMED
Turner JR, Shen LH, Crum CP, Dean PJ, Odze RD. Low prevalence of human papillomavirus infection in esophageal squamous cell carcinomas from North America: analysis by a highly sensitive and specific polymerase chain reaction-based approach. 1997. Hum Pathol. 28, 174-178
PDF PUBMED
Turner JR, Rill BK, Carlson SL, Carnes D, Kerner R, Mrsny RJ, Madara JL. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. 1997. Am J Physiol. 273, C1378-1385
PDF PUBMED
Turner JR, Skarin AT. Cancer of the gastrointestinal tract. 1996. Atlas of Diagnostic Oncology. 2nd Ed, 111-160
Tenner S, Carr-Locke DL, Banks PA, Brooks DC, Van Dam J, Farraye FA, Turner JR, Lichtenstein DR. Intraductal mucin-hypersecreting neoplasm “mucinous ductal ectasia”: endoscopic recognition and management. 1996. Am J Gastroenterol. 91, 2548-2554
PDF PUBMED
Turner JR, Odze RD. Proliferative characteristics of differentiated cells in familial adenomatous polyposis-associated duodenal adenomas. 1996. Hum Pathol. 278, 63-69
PDF PUBMED
Probert CS, Chott A, Turner JR, Saubermann LJ, Stevens AC, Bodinaku K, Elson CO, Balk SP, Blumberg RS. Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease. 1996. J Immunol. 157, 3183-3191
PDF PUBMED
Turner JR, Lencer WI, Carlson S, Madara JL. Carboxy-terminal vesicular stomatitis virus G protein-tagged intestinal Na+-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expression. 1996. J Biol Chem. 271, 7738-7744
PDF PUBMED
Turner JR, Madara JL.. Physiological regulation of intestinal epithelial tight junctions as a consequence of Na+-coupled nutrient transport. 1995. Gastroenterology. 109, 1391-1396
PDF PUBMED
Nusrat A, Giry M, Turner JR, Colgan SP, Parkos CA, Carnes D, Lemichez E, Boquet P, Madara JL. Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. 1995. Proc Natl Acad Sci U S A. 92, 10629-10633. PMC40665
PDF PUBMED
Tartakoff AM, Turner JR. The Golgi complex. 1995. Cellular Organelles and the Extracellular Matrix. 19-38
PDF
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. 1993. Int Immunol. 5, 1461-1471
PDF PUBMED
Tartakoff AM, Turner JR. The Golgi complex. 1992. Fundamentals of Medical Cell Biology. 283-304
Berger M, Wetzler EM, Welter E, Turner JR, Tartakoff AM. Intracellular sites for storage and recycling of C3b receptors in human neutrophils. 1991. Proc Natl Acad Sci U S A. 88, 3019-3023. PMC51375
PDF PUBMED
Turner JR, Tartakoff AM, Greenspan NS. Cytologic assessment of nuclear and cytoplasmic O-linked N- acetylglucosamine distribution by using anti-streptococcal monoclonal antibodies. 1990. Proc Natl Acad Sci U S A. 87, 5608-5612
PDF PUBMED
Turner JR, Tartakoff AM, Berger M. A flow-cytometric method for the quantitative analysis of intracellular and surface membrane antigens. 1989. Methods in cell biology. 32, 351-363
PDF PUBMED
Turner JR, Tartakoff AM. The response of the Golgi complex to microtubule alterations: the roles of metabolic energy and membrane traffic in Golgi complex organization. 1989. J Cell Biol. 109, 2081-2088. PMC2115848
PDF PUBMED
Turner JR, Tartakoff AM, Berger M. Intracellular degradation of the complement C3b/C4b receptor in the absence of ligand. 1988. J Biol Chem. 263, 4914-4920
PDF PUBMED
Seya T, Turner JR, Atkinson JP. Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b. 1986. J Exp Med. 163, 837-855. PMC2188078
PDF PUBMED
QA Publications.

Brigham and
Women's
Hospital

Harvard
Medical
School

© Copyright JR Turner 2020.