This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] 

Antibody charactierzation and validation (SLC5A1):

This commercial antibody from Abcam (ab14686) was raised against “synthetic peptide, corresponding to amino acids 402-422 of Human SGLT1.” Antibodies were affinity purified and detected a single band on western blot of approximately 74kDa. In formalin-fixed, paraffin-embedded tissues, localization on the apical surface of the villus of the duodenum was confirmed (right, upper image) and a decrease in expression in the apical surface of the distal colon (right, lower image).