Yan Y. Sweat, : Turner Lab

Yan Y. Sweat, Ph.D.

Postdoctoral Fellow

Publications

Oami T, Abtahi S, Shimazui T, Chen CW, Sweat YY, Liang Z, Burd EM, Farris AB, Roland JT, Tsukita S, Ford ML, Turner JR, Coopersmith CM.. Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis. 2024. Proc Natl Acad Sci U S A. 121, e2217877121. PMC10927519
PDF PUBMED
Zuo L, Kuo WT, Cao F, Chanez-Paredes SD, Zeve D, Mannam P, Jean-Francois L, Day A, Vallen Graham W, Sweat YY, Shashikanth N, Breault DT, Turner JR. Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease. 2022. Gut
PDF PUBMED
Sweat YY, Abtahi S, Chanez-Paredes SD, Raju P, Zuo L, Shashikanth N , Kuo W-T, Turner JR. Modulation of Intestinal Disorders by Claudin-2 and Occludin Via Canonical and Noncanonical Mechanisms. 2022. Tight Junctions, 3rd Edition. González-Mariscal L, Editor . 85-107
PUBMED
Zuo L, Kuo WT, Cao F, Chanez-Paredes SD, Zeve D, Mannam P, Jean-Francois L, Day A, Vallen Graham W, Sweat YY, Shashikanth N, Breault DT, Turner JR. Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease. 2022. Gut
PDF PUBMED
Sweat YY, Turner JR. PTPN2 mutations cause epithelium-intrinsic barrier loss that synergizes with mucosal immune hyperactivation. 2021. J Clin Invest. 131, e151414. PMC8409575
PDF PUBMED

Brigham and
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