Sam Nalle : Turner Lab

Sam Nalle, Ph.D.

Ph.D. Student

2007-2011

Current Position: Associate Director, Alector, Inc.

Publications

Nalle SC, Zuo L, Ong M, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. 2019. J Clin Invest. 129, 902-914. PMC6355225
SUMMARY PDF PUBMED
Nalle SC, Turner JR. Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. 2015. Mucosal Immunol. 8, 720-730
PDF PUBMED
Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR. Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. 2014. Sci Transl Med. 6, 243ra287. PMC4161673
PDF PUBMED
Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. 2013. Gastroenterology. 145, 407-415. PMC3722284
PDF PUBMED
Nalle SC, Turner JR. Endothelial and epithelial barriers in graft-versus-host disease. 2012. Biology and Regulation of Blood-Tissue Barriers. 105-131
PDF
Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. 2009. Gastroenterology. 136, 551-563. PMC2712351
PDF PUBMED
Nalle SC, Turner JR. Epithelium, tear down this wall!. 2009. Cell Host Microbe. 5, 1-2
PDF PUBMED
Nalle SC, Turner JR. Menetrier’s disease therapy: rebooting mucosal signaling. 2009. Sci Transl Med. 1, 8ps10
PDF PUBMED

Brigham and
Women's
Hospital

Harvard
Medical
School

© Copyright JR Turner 2020.