David R. Raleigh : Turner Lab

David R. Raleigh, M.D., Ph.D.

M.D.-Ph.D. (MSTP) Student

2006-2010

Current Position: Assistant Professor of Radiation Oncology
Robert and Ruth Halperin Endowed Chair in Meningioma Research
University of California, San Francisco (UCSF)

Publications

Buschmann MM, Shen L, Rajapakse H, Raleigh DR, Wang Y, Wang Y, Lingaraju A, Zha J, Abbott E, McAuley EM, Breskin LA, Wu L, Anderson K, Turner JR, Weber CR. Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. 2013. Mol Biol Cell. 24, 3056-3068. PMC3784380
PDF PUBMED
Raleigh DR, Boe DM, Yu D, Weber CR, Marchiando AM, Bradford EM, Wang Y, Wu L, Schneeberger EE, Shen L, Turner JR. Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. 2011. J Cell Biol. 193, 565-582. PMC3087007
SUMMARY PDF PUBMED
Shen L, Weber CR, Raleigh DR, Yu D, Turner JR. Tight junction pore and leak pathways: a dynamic duo. 2011. Annual review of physiology. 73, 283-309. PMC4655434
PDF PUBMED
Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR. Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. 2010. Mol Biol Cell. 21, 1200-1213. PMC2847524
PDF PUBMED
Marchiando AM, Shen L, Graham WV, Weber CR, Schwarz BT, Austin JR, 2nd, Raleigh DR, Guan Y, Watson AJ, Montrose MH, Turner JR. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. 2010. J Cell Biol. 189, 111-126. PMC2854371
PDF PUBMED
Weber CR, Raleigh DR, Su L, Shen L, Sullivan EA, Wang Y, Turner JR. Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. 2010. J Biol Chem. 285, 12037-12046. PMC2852941
PDF PUBMED
Yu D, Marchiando AM, Weber CR, Raleigh DR, Shen L, Turner JR, Wang Y. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. 2010. Proc Natl Acad Sci U S A. 107, 8237-8241. PMC2889526
PDF PUBMED

Lab Member

David R. Raleigh, M.D., Ph.D.

Publications